Kim Seong-Yeol, Roh Choong-Hee, Kim Da-Sol, Kim Gi-Wook, Won Yu Hui, Ko Myoung-Hwan, Seo Jeong-Hwan, Park Sung-Hee
Department of Physical Medicine and Rehabilitation, Jeonbuk National University Hospital, Jeonju, Korea.
Research Institute of Clinical Medicine of Jeonbuk National University - Biomedical Research Institute of Jeonbuk National University Hospital, Jeonju, Korea.
Brain Neurorehabil. 2023 Jul 27;16(2):e20. doi: 10.12786/bn.2023.16.e20. eCollection 2023 Jul.
To the best of our knowledge, the upper age limit at which post-neonatal cerebral palsy (CP) can manifest remains uncertain. This uncertainty is attributed to the lack of objective parameters for assessing the developing brain. In a previous study, we reported that an ipsilateral corticospinal projection associated with brain injury, as manifested in the paretic hand of a CP patient, had never been observed in individuals aged > 2 years. In this case report, we present an instance of ipsilateral motor evoked potential (iMEP) in a girl whose traumatic brain injury occurred at the age of 4 years. This case is the oldest in which brain injury occurred and iMEP was maintained. In conclusion, iMEP can be a valuable indicator of motor system plasticity in the developing brain.
据我们所知，新生儿期后脑性瘫痪（CP）可能出现的年龄上限仍不确定。这种不确定性归因于缺乏评估发育中大脑的客观参数。在先前的一项研究中，我们报告称，在年龄大于2岁的个体中，从未观察到与脑损伤相关的同侧皮质脊髓投射，如CP患者患侧手部所表现的那样。在本病例报告中，我们呈现了一名4岁时发生创伤性脑损伤的女孩出现同侧运动诱发电位（iMEP）的实例。该病例是脑损伤发生且iMEP持续存在的年龄最大的病例。总之，iMEP可能是发育中大脑运动系统可塑性的一个有价值的指标。
