Naji Hussein, Jayakumar Joanna, Ali Rola
Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, United Arab Emirates.
Mediclinic Parkview Hospital, Dubai, United Arab Emirates.
Surg Open Sci. 2023 Jul 27;14:120-123. doi: 10.1016/j.sopen.2023.07.018. eCollection 2023 Aug.
The objective of this study was to identify the predominant bacteria cultured from the surface of removed appendices in pediatric patients with acute appendicitis and determine the appropriate choice of antibiotics for preoperative and postoperative management.
A 2-year retrospective cohort study was conducted at Mediclinic Parkview Hospital, Dubai, UAE. Patients under 14 years of age with diagnosed acute appendicitis who underwent laparoscopic appendectomy were included. Swab cultures, along with demographic, laboratory, and pathology data, were analyzed.
Out of the 56 enrolled patients, 27 (48 %) exhibited bacterial growth on swab cultures, while 29 (52 %) showed no bacterial growth. () was the predominant isolated bacteria, present in 23/27 patients (85 %). Seven patients had co-infections involving and other bacteria, with Pseudomonas being the second most common bacteria identified in 7/27 patients (25 %). Antibiotic sensitivity testing indicated that 85 % of the isolated bacteria were sensitive to Gentamicin, 63 % to Amoxicillin/Clavulanic acid, 59 % to Trimethoprim + Sulfamethoxazole, and 27 % to Cefazolin.
was the most prevalent bacteria identified on swabs taken from inflamed appendices in pediatric patients. Amoxicillin/Clavulanic acid was determined to be an appropriate choice for preoperative prophylaxis. This study provides valuable insights for guiding the management of pediatric appendicitis and facilitating the appropriate and judicious use of antibiotics.
本研究的目的是确定急性阑尾炎患儿切除阑尾表面培养出的主要细菌,并确定术前和术后管理中抗生素的合适选择。
在阿联酋迪拜的 Mediclinic Parkview 医院进行了一项为期 2 年的回顾性队列研究。纳入 14 岁以下诊断为急性阑尾炎并接受腹腔镜阑尾切除术的患者。对拭子培养物以及人口统计学、实验室和病理学数据进行分析。
在 56 名登记患者中,27 名(48%)拭子培养物显示有细菌生长,而 29 名(52%)未显示细菌生长。(此处原文括号内容缺失)是主要分离出的细菌,存在于 23/27 名患者(85%)中。7 名患者有合并感染,涉及(此处原文缺失)和其他细菌,铜绿假单胞菌是在 7/27 名患者(25%)中鉴定出的第二常见细菌。抗生素敏感性测试表明,85%的分离细菌对庆大霉素敏感,63%对阿莫西林/克拉维酸敏感,59%对甲氧苄啶 + 磺胺甲恶唑敏感,27%对头孢唑林敏感。
(此处原文缺失)是在儿科患者发炎阑尾拭子上鉴定出的最普遍细菌。阿莫西林/克拉维酸被确定为术前预防的合适选择。本研究为指导小儿阑尾炎的管理和促进抗生素的合理明智使用提供了有价值的见解。