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一名有神经学和血液学表现的婴儿维生素B12缺乏症:病例报告。

Vitamin B12 deficiency in an infant with neurological and hematological findings: A case report.

作者信息

Sharma Niraj Kumar, Bhattarai Madhur, Baral Kushal, Poudel Susmita, Hassan Nusaiba Farouk, Dhakal Tulsi Ram, Baral Rituraj

机构信息

Institute of Medicine Tribhuvan University Kathmandu Nepal.

Chitwan Medical College Bharatpur Nepal.

出版信息

Clin Case Rep. 2023 Aug 7;11(8):e7770. doi: 10.1002/ccr3.7770. eCollection 2023 Aug.

Abstract

KEY CLINICAL MESSAGE

It is important for pregnant and breastfeeding women who adhere to a strict vegetarian diet to take appropriate steps to avoid vitamin B12 deficiency in their infants.

ABSTRACT

Vitamin B12 deficiency is rare during infancy. The initial symptoms of this deficiency are subtle and may include irritability, failure to thrive with a decline in growth rate, apathy, anorexia, refusal of solid foods, megaloblastic anemia, and developmental regression. The case presented here involves an 8-month-old male infant who showed neurological symptoms such as decreased activity, increased drowsiness, and reduced interaction with parents, which were ultimately linked to a deficiency of cobalamin (vitamin B12). Early recognition of this condition is critical because it is reversible. Therefore, pregnant and lactating women who follow a strict vegetarian diet should take necessary measures to prevent vitamin B12 deficiency in infants.

摘要

关键临床信息

坚持严格素食饮食的孕妇和哺乳期妇女采取适当措施避免婴儿维生素B12缺乏非常重要。

摘要

婴儿期维生素B12缺乏很少见。这种缺乏的初始症状很细微,可能包括易怒、生长速度下降导致发育不良、冷漠、厌食、拒绝固体食物、巨幼细胞贫血和发育倒退。这里呈现的病例是一名8个月大的男婴,表现出活动减少、嗜睡增加以及与父母互动减少等神经症状,这些最终与钴胺素(维生素B12)缺乏有关。早期识别这种情况至关重要,因为它是可逆的。因此,遵循严格素食饮食的孕妇和哺乳期妇女应采取必要措施预防婴儿维生素B12缺乏。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1081/10405240/ad01125ee1de/CCR3-11-e7770-g001.jpg

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