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乳糜泻的非活检诊断方法。

No-biopsy diagnostic approach to coeliac disease.

作者信息

Holmes Geoffrey

机构信息

Department of Gastroenterology, Royal Derby Hospital, Derby, UK.

出版信息

Gastroenterol Hepatol Bed Bench. 2023;16(2):112-117. doi: 10.22037/ghfbb.v16i2.2706.

DOI:10.22037/ghfbb.v16i2.2706
PMID:37554754
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10404819/
Abstract

This brief review outlines contributions that Michael Marsh and others made to understanding the structure and function of the upper small bowel mucosa and the formation of abnormalities that occur in coeliac disease (CD). He introduced his classification of lesions 30 years ago that has been widely adopted. The development and use of serological tests to screen for and diagnose CD in children and adults without the need for a small bowel biopsy in a considerable proportion is also recognised and will gain traction.

摘要

本简要综述概述了迈克尔·马什等人对理解上段小肠黏膜的结构和功能以及乳糜泻（CD）中出现的异常形成所做的贡献。他在30年前提出了已被广泛采用的病变分类法。血清学检测在儿童和成人中用于筛查和诊断CD的发展及应用也得到认可，在相当大比例的情况下无需进行小肠活检，且这一方法将会更受关注。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9436/10404819/d2052c8b6ccd/GHFBB-16-112-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9436/10404819/ea8bb2a07bbc/GHFBB-16-112-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9436/10404819/39b1a8a2df62/GHFBB-16-112-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9436/10404819/d2052c8b6ccd/GHFBB-16-112-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9436/10404819/ea8bb2a07bbc/GHFBB-16-112-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9436/10404819/39b1a8a2df62/GHFBB-16-112-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9436/10404819/d2052c8b6ccd/GHFBB-16-112-g003.jpg

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1
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2
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本文引用的文献

1
No-biopsy strategy for coeliac disease is applicable in adult patients: a 'real-world' Scottish experience.成人腹腔疾病的非活检策略适用：苏格兰的“真实世界”经验
Frontline Gastroenterol. 2022 Aug 11;14(2):97-102. doi: 10.1136/flgastro-2022-102254. eCollection 2023.
2
Gluten Induces Subtle Histological Changes in Duodenal Mucosa of Patients with Non-Coeliac Gluten Sensitivity: A Multicentre Study. gluten 诱导非乳糜泻麸质敏感性患者十二指肠黏膜的细微组织学变化：一项多中心研究。
Nutrients. 2022 Jun 15;14(12):2487. doi: 10.3390/nu14122487.
3
Is duodenal biopsy always necessary for the diagnosis of coeliac disease in adult patients with high anti-tissue transglutaminase (TTG) antibody titres?
对于抗组织转谷氨酰胺酶（TTG）抗体滴度高的成年腹腔疾病患者，十二指肠活检对于诊断是否总是必要的？
Frontline Gastroenterol. 2021 Jun 25;13(4):287-294. doi: 10.1136/flgastro-2020-101728. eCollection 2022.
4
No-biopsy pathway following the interim BSG guidance reliably diagnoses adult coeliac disease.遵循英国胃肠病学会（BSG）临时指南的无活检途径可可靠诊断成人乳糜泻。
Frontline Gastroenterol. 2020 Oct 6;13(1):73-76. doi: 10.1136/flgastro-2020-101624. eCollection 2022.
5
Accuracy of a no-biopsy approach for the diagnosis of coeliac disease across different adult cohorts.不同成人队列中无活检方法诊断乳糜泻的准确性。
Gut. 2021 May;70(5):876-883. doi: 10.1136/gutjnl-2020-320913. Epub 2020 Nov 2.
6
European Society Paediatric Gastroenterology, Hepatology and Nutrition Guidelines for Diagnosing Coeliac Disease 2020.欧洲儿科胃肠病学、肝病学和营养学学会 2020 年乳糜泻诊断指南。
J Pediatr Gastroenterol Nutr. 2020 Jan;70(1):141-156. doi: 10.1097/MPG.0000000000002497.
7
Diagnosing celiac disease: A critical overview.乳糜泻的诊断：批判性综述。
Turk J Gastroenterol. 2019 May;30(5):389-397. doi: 10.5152/tjg.2018.18635.
8
Serology-based criteria for adult coeliac disease have excellent accuracy across the range of pre-test probabilities.基于血清学的成人乳糜泻诊断标准在各种术前概率范围内具有优异的准确性。
Aliment Pharmacol Ther. 2019 Feb;49(3):277-284. doi: 10.1111/apt.15109. Epub 2018 Dec 27.
9
The serological diagnosis of coeliac disease - a step forward.乳糜泻的血清学诊断——向前迈进的一步。
Gastroenterol Hepatol Bed Bench. 2018 Summer;11(3):209-215.
10
Evidence Supporting Serology-based Pathway for Diagnosing Celiac Disease in Asymptomatic Children From High-risk Groups.支持基于血清学方法诊断高危无症状儿童乳糜泻的证据。
J Pediatr Gastroenterol Nutr. 2018 Apr;66(4):641-644. doi: 10.1097/MPG.0000000000001757.