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妊娠期双侧温德利希综合征导致佩吉氏肾:一例罕见病例报告

Bilateral Wunderlich syndrome causing Page kidney during pregnancy: a rare case report.

作者信息

Alsayed-Ahmad Zein A, Roumi Jamal Bakri, Bouzan Dania, Helou Muhammad H, Albitar Sami

机构信息

Faculty of Medicine.

Department of Nephrology, Faculty of Medicine, Aleppo University Hospital, University of Aleppo, Aleppo, Syria.

出版信息

Ann Med Surg (Lond). 2023 Jul 8;85(8):4157-4160. doi: 10.1097/MS9.0000000000001062. eCollection 2023 Aug.

Abstract

UNLABELLED

Wunderlich syndrome is a rare and life-threatening condition that is characterized by spontaneous renal hemorrhage into the subcapsular and perinephric regions. This case report describes the diagnosis and management of bilateral Wunderlich syndrome during pregnancy, resulting in Page kidney.

CASE PRESENTATION

The patient presented with complaints of left flank pain and breathlessness. After stabilization, an emergency lower cesarean delivery was performed, and a percutaneous drainage procedure was carried out to alleviate the compression on the left kidney. The patient was treated with blood transfusion, methyldopa, and perindopril. Follow-up examinations performed 3 months later revealed a significant decrease in fluid volume surrounding the left kidney.

CLINICAL DISCUSSION

Lenk's triad provides the primary description of the classical manifestations of this syndrome. Some instances have been connected to the Page kidney phenomenon. The relationship between pregnancy and Wunderlich syndrome has not been extensively studied, primarily because the symptoms can resemble other complications related to pregnancy. Due to the scarcity of evidence in the literature, there is no definitive guideline for managing Wunderlich syndrome during pregnancy. Consequently, each patient is treated on an individual basis. Conservative treatment is recommended once malignancy has been ruled out.

CONCLUSION

The case highlights the importance of considering Wunderlich syndrome as a differential diagnosis in pregnant patients with abdominal or flank pain, a palpable mass, and hypovolemia. Furthermore, the case illustrates the successful management of Wunderlich syndrome during pregnancy.

摘要

未标注

温德利希综合征是一种罕见且危及生命的疾病,其特征为肾脏自发出血至肾包膜下和肾周区域。本病例报告描述了孕期双侧温德利希综合征的诊断和治疗,最终导致佩奇肾。

病例介绍

患者因左侧腰痛和呼吸急促就诊。病情稳定后,进行了急诊低位剖宫产,并实施了经皮引流术以减轻对左肾的压迫。患者接受了输血、甲基多巴和培哚普利治疗。3个月后进行的随访检查显示左肾周围液体量显著减少。

临床讨论

伦克三联征对该综合征的经典表现进行了初步描述。一些病例与佩奇肾现象有关。妊娠与温德利希综合征之间的关系尚未得到广泛研究,主要是因为其症状可能与妊娠相关的其他并发症相似。由于文献中证据稀少,孕期温德利希综合征的管理尚无明确指南。因此,对每个患者都进行个体化治疗。一旦排除恶性肿瘤,建议采取保守治疗。

结论

该病例强调了在有腹痛或腰痛、可触及肿块和血容量不足的孕妇中将温德利希综合征作为鉴别诊断的重要性。此外,该病例说明了孕期温德利希综合征的成功管理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/74d0/10405985/b4489fd9de99/ms9-85-4157-g001.jpg

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