Ocak Tuğba, Gülten Macit
Department of Internal Medicine, Uludağ University Medical School, Bursa, Turkey.
Department of Gastroenterology, Uludağ University Medical School, Bursa, Turkey.
Euroasian J Hepatogastroenterol. 2023 Jan-Jun;13(1):5-9. doi: 10.5005/jp-journals-10018-1387.
Spontaneous bacterial peritonitis (SBP) is an important reason for mortality in cirrhosis. This study aimed to identify the factors associated with mortality in SBP.
A total of 69 patients with cirrhosis and 74 with SBP attacks that occurred in this group were assessed. Demographic data, symptoms at admission, comorbidities, laboratory parameters, treatment protocols, causes of cirrhosis, scoring characteristics, cirrhosis complications, and mortality were analyzed.
Model for end-stage liver disease (MELD; = 0.001), sodium-MELD ( = 0.001), and Child-Pugh-Turcotte (CTP) ( < 0.001) scores were correlated with mortality in patients with SBP episodes. Hepatorenal syndrome ( = 0.001) and esophageal variceal bleeding ( < 0.001) related to mortality. Serum lactate dehydrogenase (LDH) ( = 0.007), serum leukocyte ( = 0.017), and serum hemoglobin ( = 0.010) values had a statistically significant effect on mortality in multivariate regression analysis.
The mortality rate can be reduced by identifying factors influencing death in patients with SBP episodes.
Ocak T, Gülten M. Retrospective Investigation of Factors Affecting Mortality in Spontaneous Bacterial Peritonitis. Euroasian J Hepato-Gastroenterol 2023;13(1):5-9.
自发性细菌性腹膜炎（SBP）是肝硬化患者死亡的重要原因。本研究旨在确定与SBP患者死亡率相关的因素。
对69例肝硬化患者及该组中发生的74次SBP发作进行评估。分析人口统计学数据、入院时症状、合并症、实验室参数、治疗方案、肝硬化病因、评分特征、肝硬化并发症及死亡率。
终末期肝病模型（MELD；P = 0.001）、钠-MELD（P = 0.001）和Child-Pugh-Turcotte（CTP）评分（P < 0.001）与SBP发作患者的死亡率相关。肝肾综合征（P = 0.001）和食管静脉曲张破裂出血（P < 0.001）与死亡率相关。在多因素回归分析中，血清乳酸脱氢酶（LDH）（P = 0.007）、血清白细胞（P = 0.017）和血清血红蛋白（P = 0.010）值对死亡率有统计学显著影响。
通过识别影响SBP发作患者死亡的因素可降低死亡率。
Ocak T, Gülten M. 自发性细菌性腹膜炎死亡率影响因素的回顾性研究. 《欧亚肝脏胃肠病学杂志》2023；13(1):5-9。
