一名免疫抑制患者的急性肝炎：一个难题。
Acute Hepatitis in an Immunosuppressed Patient: A Dilemma.
作者信息
Gupta Tarana
机构信息
Department of Medicine, Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana, India.
出版信息
Euroasian J Hepatogastroenterol. 2023 Jan-Jun;13(1):26-27. doi: 10.5005/jp-journals-10018-1368.
UNLABELLED
Acute hepatitis in patients on chemotherapy has always been challenging. Demystifying the truth becomes essential to continue chemotherapy. Wepresent a case of carcinoma buccal mucosa who developed acute hepatitis following a single dose of cisplatin and radiotherapy. In the background of a history of chronic alcoholism, and alcohol abstinence of more than 3 months, acute alcoholic hepatitis was unlikely. Though he had occult hepatitis B with HBsAg negative and positive IgG anti-HBc antibody status, however, with undetectable HBV DNA PCR quantitative, hepatitis B was unlikely to be the cause of acute hepatitis. With all viral markers including atypical viruses and autoimmune work-up being negative, it was a real-time challenge to find the exact cause.
HOW TO CITE THIS ARTICLE
Gupta T. Acute Hepatitis in an Immunosuppressed Patient: A Dilemma. Euroasian J Hepato-Gastroenterol 2023;13(1):26-27.
未标注
化疗患者出现急性肝炎一直具有挑战性。揭开真相对于继续化疗至关重要。我们报告一例颊黏膜癌患者，在单次使用顺铂和放疗后发生急性肝炎。在有慢性酒精中毒史且戒酒超过3个月的背景下，急性酒精性肝炎可能性不大。虽然他存在隐匿性乙型肝炎，乙肝表面抗原阴性但IgG抗-HBc抗体阳性，然而，乙肝病毒DNA聚合酶链反应定量检测不到，乙型肝炎不太可能是急性肝炎的病因。所有病毒标志物包括非典型病毒及自身免疫检查均为阴性，要找出确切病因是一项现实挑战。
如何引用本文
古普塔T。免疫抑制患者的急性肝炎：一个困境。《欧亚肝脏胃肠病学杂志》2023年；13(1)：26 - 27。
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