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唐氏综合征患儿神经发育结局的纵向预测因素。

Longitudinal Predictors of Neurodevelopmental Outcomes in Children with Down Syndrome.

机构信息

Department of Human Development and Family Studies, Colorado State University, Fort Collins, Colorado, USA.

Department of Psychology, Colorado State University, Fort Collins, Colorado, USA.

出版信息

Dev Neuropsychol. 2023 Aug 18;48(6):280-298. doi: 10.1080/87565641.2023.2239401. Epub 2023 Aug 9.

Abstract

This study examined longitudinal predictors of neurodevelopmental outcomes in children with Down syndrome (DS). Participants were assessed at Wave 1 during infancy on measures of looking behavior and caregivers provided infant sensory ratings. At Wave 2, child-age participants completed a developmental assessment and caregivers provided ratings of executive function, ADHD symptoms, and autism symptoms. Longer looking durations and greater sensory dysregulation during infancy were predictive of higher ADHD symptom ratings and other neurodevelopmental outcomes during childhood. The findings suggest that early indicators of neurodevelopmental dysregulation may be detectable during infancy in DS.

摘要

本研究考察了唐氏综合征(DS)儿童神经发育结果的纵向预测因素。参与者在婴儿期的第 1 波接受了注视行为的评估,照顾者提供了婴儿感觉评分。在第 2 波,儿童年龄的参与者完成了发育评估,照顾者提供了执行功能、ADHD 症状和自闭症症状的评分。婴儿期注视时间延长和感觉调节障碍越大,ADHD 症状评分和儿童期其他神经发育结果越高。研究结果表明,神经发育失调的早期指标可能在 DS 婴儿期就可以检测到。

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Infant precursors of executive function in Down syndrome.唐氏综合征中执行功能的婴儿前体。
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本文引用的文献

1
Early developmental profiles among infants with Down syndrome.唐氏综合征婴儿的早期发育概况。
J Intellect Disabil Res. 2023 Mar;67(3):228-238. doi: 10.1111/jir.12997. Epub 2022 Dec 9.
5
Infant precursors of executive function in Down syndrome.唐氏综合征中执行功能的婴儿前体。
J Intellect Disabil Res. 2022 Jan;66(1-2):108-120. doi: 10.1111/jir.12824. Epub 2021 Mar 2.
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Down Syndrome.唐氏综合征
N Engl J Med. 2020 Jun 11;382(24):2344-2352. doi: 10.1056/NEJMra1706537.

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