Thoracic Surgery Unit, University of Campania Luigi Vanvitelli, Caserta, Italy.
S.C. Sarcomi e Tumori Rari, Istituto Nazionale Tumori-IRCCS-Fondazione "G. Pascale", Naples, Italy.
Thorac Cancer. 2023 Sep;14(26):2712-2714. doi: 10.1111/1759-7714.15064. Epub 2023 Aug 9.
Complex persistent air leak (PAL) is a clinical condition which is difficult to treat. Herein, we report the clinical case of an 18-year-old woman with lung and bone metastases due an ultrarare sarcoma: "round cell sarcoma non-Ewing". She developed persistent air leaks due to an alveolopleural fistula which developed following two cycles of chemotherapy with doxorubicin. Chest drainage with suction failed to resolve the air leaks, while surgical treatment was unfeasible due to the poor clinical condition of the patient. Thus, she was reviewed for endoscopic treatment with one-way endobronchial valves. A small valve was sequentially inserted within each segment of the right upper bronchus to occlude the entire upper lobe. Two days after the procedure, resolution of the air leaks were obtained. Chest drainage was removed 5 days later and the patient was discharged. Chemotherapy was resumed. The patient died 7 months later because of disease progression.
复杂持续性肺漏气（PAL）是一种临床治疗较为困难的病症。在此，我们报告一例 18 岁女性的病例，该患者患有极为罕见的肉瘤导致肺部和骨转移：“圆形细胞肉瘤非尤文氏瘤”。她在接受两个周期多柔比星化疗后发生肺泡-胸膜瘘，导致持续性肺漏气。胸腔引流并不能解决漏气问题，而由于患者的临床状况较差，手术治疗也不可行。因此，对她进行了内镜单向支气管内瓣膜治疗的审查。一个小阀门被依次插入右上支气管的各个节段以阻塞整个上叶。该操作两天后，漏气得到解决。5 天后，胸腔引流被移除，患者出院。随后继续化疗。7 个月后，患者因疾病进展而死亡。
