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本文引用的文献

1
Formation of secondary allo-bile acids by novel enzymes from gut Firmicutes.肠道Firmicutes 新型酶形成次级胆汁酸。
Gut Microbes. 2022 Jan-Dec;14(1):2132903. doi: 10.1080/19490976.2022.2132903.
2
C-section increases cecal abundance of the archetypal bile acid and glucocorticoid modifying Lachnoclostridium [clostridium] scindens in mice.剖宫产术增加了小鼠典型胆汁酸和糖皮质激素修饰的lachnoclostridium[梭菌属]scindens 的盲肠丰度。
Physiol Rep. 2022 Jul;10(13):e15363. doi: 10.14814/phy2.15363.
3
Canu: scalable and accurate long-read assembly via adaptive -mer weighting and repeat separation.Canu：通过自适应k-mer加权和重复序列分离实现可扩展且准确的长读长序列拼接
Genome Res. 2017 May;27(5):722-736. doi: 10.1101/gr.215087.116. Epub 2017 Mar 15.
4
BUSCO: assessing genome assembly and annotation completeness with single-copy orthologs.BUSCO：利用单拷贝同源基因评估基因组组装和注释的完整性。
Bioinformatics. 2015 Oct 1;31(19):3210-2. doi: 10.1093/bioinformatics/btv351. Epub 2015 Jun 9.
5
Prokka: rapid prokaryotic genome annotation.Prokka：快速的原核生物基因组注释。
Bioinformatics. 2014 Jul 15;30(14):2068-9. doi: 10.1093/bioinformatics/btu153. Epub 2014 Mar 18.
6
Isolation and characterization of a bile acid inducible 7alpha-dehydroxylating operon in Clostridium hylemonae TN271.从 Clostridium hylemonae TN271 中分离并鉴定胆汁酸诱导的 7α-脱羟化酶操纵子。
Anaerobe. 2010 Apr;16(2):137-46. doi: 10.1016/j.anaerobe.2009.05.004. Epub 2009 May 21.
7
Development of methods for the detection and quantification of 7alpha-dehydroxylating clostridia, Desulfovibrio vulgaris, Methanobrevibacter smithii, and Lactobacillus plantarum in human feces.人类粪便中7α-脱羟基梭菌、普通脱硫弧菌、史氏甲烷短杆菌和植物乳杆菌的检测与定量方法的开发。
Clin Chim Acta. 2005 Jul 1;357(1):55-64. doi: 10.1016/j.cccn.2005.02.004. Epub 2005 Apr 1.
8
Assignment of Eubacterium sp. VPI 12708 and related strains with high bile acid 7alpha-dehydroxylating activity to Clostridium scindens and proposal of Clostridium hylemonae sp. nov., isolated from human faeces.将具有高胆汁酸7α-脱羟基活性的真杆菌属VPI 12708菌株及相关菌株归为梭状芽孢杆菌，并提出从人粪便中分离出的新种梭状芽孢杆菌。
Int J Syst Evol Microbiol. 2000 May;50 Pt 3:971-978. doi: 10.1099/00207713-50-3-971.
9
Purification and characterization of a novel 17 alpha-hydroxysteroid dehydrogenase from an intestinal Eubacterium sp. VPI 12708.从肠道真杆菌VPI 12708中纯化并鉴定一种新型17α-羟基类固醇脱氢酶
J Lipid Res. 1994 May;35(5):922-9.
10
7 alpha-Dehydroxylation of cholic acid by cell extracts of Eubacterium species V.P.I. 12708.真杆菌属V.P.I. 12708菌株细胞提取物对胆酸的7α-脱羟基作用
Am J Clin Nutr. 1980 Nov;33(11 Suppl):2507-10. doi: 10.1093/ajcn/33.11.2507.

1980年前后从人类粪便中分离出的原型胆汁酸7α-脱羟基化细菌VPI12708的全基因组序列。

Complete genome sequence of the archetype bile acid 7α-dehydroxylating bacterium, VPI12708, isolated from human feces, circa 1980.

作者信息

Olivos Caicedo Kelly Yovani, Fernandez-Materan Francelys V, Hernandez Alvaro G, Daniel Steven L, Alves Joao M P, Ridlon Jason M

机构信息

Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo , São Paulo, Brazil.

Carl R. Woese Institute for Genomic Biology, University of Illinois Urbana-Champaign , Urbana, Illinois, USA.

出版信息

Microbiol Resour Announc. 2023 Sep 19;12(9):e0002923. doi: 10.1128/MRA.00029-23. Epub 2023 Aug 9.

DOI:10.1128/MRA.00029-23
PMID:37555681
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10508169/
Abstract

strain VPI12708 serves as model organism to study bile acid 7α-dehydroxylating pathways. The closed circular genome of VPI12708 was obtained by PacBio sequencing. The genome is composed of 3,983,052 bp, with 47.59% G + C, and 3,707 coding DNA sequences are predicted.

摘要

菌株VPI12708作为研究胆汁酸7α-脱羟基化途径的模式生物。VPI12708的闭合环状基因组通过PacBio测序获得。该基因组由3,983,052个碱基对组成，G + C含量为47.59%，预测有3,707个编码DNA序列。