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从人类粪便中分离出的9株菌株的基因组序列。

Genome sequences of nine strains isolated from human feces.

作者信息

Fernandez-Materan Francelys V, Olivos-Caicedo Kelly Yovani, Daniel Steven L, Walden Kimberly K O, Fields Christopher J, Hernandez Alvaro G, Alves Joao M P, Ridlon Jason M

机构信息

Carl R. Woese Institute for Genomic Biology, University of Illinois Urbana-Champaign, Urbana, Illinois, USA.

Department of Animal Sciences, University of Illinois Urbana-Champaign, Urbana, Illinois, USA.

出版信息

Microbiol Resour Announc. 2024 Dec 12;13(12):e0084824. doi: 10.1128/mra.00848-24. Epub 2024 Nov 4.

DOI:10.1128/mra.00848-24
PMID:39494879
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11636285/
Abstract

is an important member of the gut microbiome. Strains of are model organisms for bile acid and steroid metabolism studies. The genome sequences for nine strains isolated from human feces are reported. Genomes ranged from 3,403,497 to 4,318,168 bp, 46.5% to 48% G+C content, and 3,386 to 4,137 protein-coding total genes.

摘要

是肠道微生物群的重要成员。的菌株是胆汁酸和类固醇代谢研究的模式生物。报道了从人类粪便中分离出的9种菌株的基因组序列。基因组范围从3,403,497到4,318,168碱基对，G+C含量为46.5%至48%，总蛋白编码基因有3,386至4,137个。

相似文献

[1]
Genome sequences of nine strains isolated from human feces.

Microbiol Resour Announc. 2024-12-12

[2]
Pangenome analysis of : a collection of diverse bile acid and steroid metabolizing commensal gut bacterial strains.

bioRxiv. 2024-9-6

[3]
Pangenome Analysis of : A Collection of Diverse Bile Acid- and Steroid-Metabolizing Commensal Gut Bacterial Strains.

Microorganisms. 2025-4-9

[4]
Assignment of Eubacterium sp. VPI 12708 and related strains with high bile acid 7alpha-dehydroxylating activity to Clostridium scindens and proposal of Clostridium hylemonae sp. nov., isolated from human faeces.

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[5]
Complete genome sequence of the archetype bile acid 7α-dehydroxylating bacterium, VPI12708, isolated from human feces, circa 1980.

Microbiol Resour Announc. 2023-9-19

[6]
Clostridium scindens: history and current outlook for a keystone species in the mammalian gut involved in bile acid and steroid metabolism.

FEMS Microbiol Rev. 2025-1-14

[7]
Clostridium scindens ATCC 35704: Integration of Nutritional Requirements, the Complete Genome Sequence, and Global Transcriptional Responses to Bile Acids.

Appl Environ Microbiol. 2019-3-22

[8]
: an endocrine keystone species in the mammalian gut.

bioRxiv. 2024-8-24

[9]
Strain-dependent induction of primary bile acid 7-dehydroxylation by cholic acid.

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[10]
exacerbates experimental necrotizing enterocolitis via upregulation of the apical sodium-dependent bile acid transporter.

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引用本文的文献

[1]
Clostridium scindens: history and current outlook for a keystone species in the mammalian gut involved in bile acid and steroid metabolism.

FEMS Microbiol Rev. 2025-1-14

[2]
Pangenome Analysis of : A Collection of Diverse Bile Acid- and Steroid-Metabolizing Commensal Gut Bacterial Strains.

Microorganisms. 2025-4-9

[3]
An expanded metabolic pathway for androgen production by commensal bacteria.

Nat Microbiol. 2025-5

本文引用的文献

[1]
Complete genome sequence of the archetype bile acid 7α-dehydroxylating bacterium, VPI12708, isolated from human feces, circa 1980.

Microbiol Resour Announc. 2023-9-19

[2]
The Hylemon-Björkhem pathway of bile acid 7-dehydroxylation: history, biochemistry, and microbiology.

J Lipid Res. 2023-8

[3]
Assembly of long, error-prone reads using repeat graphs.

Nat Biotechnol. 2019-4-1

[4]
The and genes from ATCC 35704 encode steroid-17,20-desmolase.

J Lipid Res. 2018-3-23

[5]
BUSCO Applications from Quality Assessments to Gene Prediction and Phylogenomics.

Mol Biol Evol. 2018-3-1

[6]
Completing bacterial genome assemblies with multiplex MinION sequencing.

Microb Genom. 2017-9-14

[7]
Unicycler: Resolving bacterial genome assemblies from short and long sequencing reads.

PLoS Comput Biol. 2017-6-8

[8]
SeqKit: A Cross-Platform and Ultrafast Toolkit for FASTA/Q File Manipulation.

PLoS One. 2016-10-5

[9]
Bandage: interactive visualization of de novo genome assemblies.

Bioinformatics. 2015-10-15

[10]
Trimmomatic: a flexible trimmer for Illumina sequence data.

Bioinformatics. 2014-4-1

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