首例感染禽流感 A/H3N8 病毒后死亡的人类病例：中国广东省，2023 年 3 月。
First Known Human Death After Infection With the Avian Influenza A/H3N8 Virus: Guangdong Province, China, March 2023.
机构信息
Institute of Infectious Disease Control and Prevention, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, Guangdong, P.R. China.
General Office, Zhongshan Center for Disease Control and Prevention, Zhongshan, Guangdong, P.R. China.
出版信息
Clin Infect Dis. 2024 Mar 20;78(3):646-650. doi: 10.1093/cid/ciad462.
Here, we report on a case of human infection with the H3N8 avian influenza virus. The patient had multiple myeloma and died of severe infection. Genome analysis showed multiple gene mutations and reassortments without mammalian-adaptive mutations. This suggests that avian influenza (A/H3N8) virus infection could be lethal for immunocompromised persons.
这里，我们报告了一例人类感染 H3N8 禽流感病毒的病例。该患者患有多发性骨髓瘤，因严重感染而死亡。基因组分析显示，存在多种基因突变和重配，但没有哺乳动物适应性突变。这表明禽流感（A/H3N8）病毒感染可能对免疫功能低下者具有致命性。
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