Department of Surgery, McMaster University, Hamilton, ON, Canada.
Cumming School of Medicine, University of Calgary, Calgary, Canada.
Ann Surg Oncol. 2023 Oct;30(11):6386-6397. doi: 10.1245/s10434-023-13912-7. Epub 2023 Aug 9.
Phyllodes tumors are rare breast neoplasms with limited prospective data to guide treatment, leading to heterogeneous management of this disease. We developed National consensus statements using modified Delphi methodology including patients and practitioners across Canada.
Statements were developed based on a literature review. Two iterations of surveys were distributed with a planned virtual consensus meeting. Panelists were invited from surgery, radiation oncology, medical oncology, pathology, radiology, and plastic surgery.
Twenty-three participants attended the virtual conference. One hundred statements regarding diagnostics, pathology, surgical planning, adjuvant therapies, recurrence, surveillance, and patient support were approved with an a priori defined consensus of ≥ 80%. Two tables on locoregional management were developed and approved. The management of borderline phyllodes tumors was a source of uncertainty, and recommendations reflect the lack of evidence in this rare presentation.
A consensus document containing all approved statements for the care and management of phyllodes tumors was developed to help guide practice and future research.
叶状肿瘤是一种罕见的乳腺肿瘤，其前瞻性数据有限，难以指导治疗，导致该病的治疗方法存在差异。我们使用改良 Delphi 方法制定了国家共识声明，其中包括加拿大各地的患者和从业者。
根据文献综述制定声明。进行了两轮调查，并计划举行虚拟共识会议。邀请了来自外科、放射肿瘤学、肿瘤内科、病理学、放射学和整形外科学领域的专家参加。
23 名参与者参加了虚拟会议。就诊断、病理学、手术计划、辅助治疗、复发、监测和患者支持等方面的 100 项声明获得了批准，预先确定的共识≥80%。制定并批准了两份关于局部区域管理的表格。交界性叶状肿瘤的管理存在不确定性，建议反映了这种罕见表现缺乏证据的情况。
制定了一份包含叶状肿瘤护理和管理所有批准声明的共识文件，以帮助指导实践和未来的研究。
