Department of Radiology, Affiliated Zhoupu Hospital, Shanghai Medical University and Health Science.
Tohoku J Exp Med. 2023 Oct 24;261(2):165-171. doi: 10.1620/tjem.2023.J065. Epub 2023 Aug 10.
Coronary artery ectasia (CAE) is defined as segmental dilatation with a diameter of 1.5-fold greater than that of an adjacent normal segment. Whether CAE is a unique clinical finding or results from other clinical entities remains to be determined. The purpose of the study was to investigate the prevalence, and clinical and angiographic characteristics of CAE in patients with coronary artery disease (CAD). Among the 8,845 coronary angiograms reviewed between the years 2014 and 2022, 142 patients had CAE yielding a detection rate of 4.9% among 2,870 CAD angiograms, and 28 patients had isolated CAE showing a detection rate of 0.32% (28/8,845) among total coronary angiography procedures. Overall, the incidence of CAE was 1.92% (170/8,845). The most commonly affected coronary artery by ectasia was the right coronary artery (RCA) (46.28%) among CAE coexisting with CAD cohort. The proportion of obesity, family history of CAD, and the proportion of hyperlipidemia in CAD patients who had ectasia were significantly higher than that in CAD patients who did not have ectasia (P < 0.05). In conclusion, CAE is an uncommon finding in coronary angiography, most commonly affecting the RCA. The obesity, family history of CAD, and the coexistence of hyperlipidemia were independent variables associated with CAE in CAD patients.
冠状动脉扩张症（CAE）定义为节段性扩张，直径大于相邻正常节段的 1.5 倍。CAE 是否是一种独特的临床发现，还是源于其他临床实体，仍有待确定。本研究旨在探讨冠状动脉疾病（CAD）患者中 CAE 的患病率、临床和血管造影特征。在 2014 年至 2022 年期间进行的 8845 例冠状动脉造影中，有 142 例患者存在 CAE，在 2870 例 CAD 血管造影中检出率为 4.9%，28 例患者存在孤立性 CAE，在总冠状动脉造影检查中检出率为 0.32%（28/8845）。总体而言，CAE 的发生率为 1.92%（170/8845）。在 CAE 合并 CAD 队列中，扩张最常见的冠状动脉是右冠状动脉（RCA）（46.28%）。在存在扩张的 CAD 患者中，肥胖、CAD 家族史和高脂血症的比例明显高于不存在扩张的 CAD 患者（P<0.05）。总之，CAE 在冠状动脉造影中是一种不常见的发现，最常影响 RCA。肥胖、CAD 家族史和高脂血症共存是 CAD 患者发生 CAE 的独立变量。
