Centre for Mathematical Modelling of Infectious Disease, London School of Hygiene and Tropical Medicine, London, UK.
BMC Med. 2023 Aug 9;21(1):301. doi: 10.1186/s12916-023-02996-3.
We recently published an article in BMC Medicine looking at the potential health and economic impact of paediatric vaccination using next-generation influenza vaccines in Kenya: a modelling study. In their commentary on our article, Lafond et al. highlight the potential importance of the wider benefits of vaccination on cost-effectiveness. Whilst we agree with many points raised in the commentary, we think it raises further interesting discussion points, specifically around model complexity, model assumptions and data availability. These points are both relevant to this manuscript but have wider implications for vaccine cost-effectiveness studies.
我们最近在《BMC 医学》杂志上发表了一篇文章,研究了在肯尼亚使用下一代流感疫苗对儿童进行免疫接种的潜在健康和经济影响:一项建模研究。在他们对我们文章的评论中,Lafond 等人强调了疫苗接种对成本效益的更广泛益处的潜在重要性。虽然我们同意评论中提出的许多观点,但我们认为这提出了进一步有趣的讨论点,特别是在模型复杂性、模型假设和数据可用性方面。这些观点不仅与本文有关,而且对疫苗成本效益研究具有更广泛的意义。