Zhang Silu, Jin Shuo, Zhang Cui, Hu Shumin, Li Huajun
Department of Microecology, Dalian Medical University, Dalian, China.
State Key Laboratory of Biological Fermentation Engineering of Beer, Tsingtao Brewery Co. Ltd., Qingdao, China.
Front Nutr. 2023 Jul 25;10:1186927. doi: 10.3389/fnut.2023.1186927. eCollection 2023.
As a long-established fermented beverage, beer is rich in many essential amino acids, vitamins, trace elements, and bioactive substances that are involved in the regulation of many human physiological functions. The polyphenols in the malt and hops of beer are also important active compounds that interact in both directions with the gut microbiome. This review summarizes the mechanisms by which polyphenols, fiber, and other beneficial components of beer are fermentatively broken down by the intestinal microbiome to initiate the mucosal immune barrier and thus participate in immune regulation. Beer degradation products have anti-inflammatory, anticoagulant, antioxidant, and glucolipid metabolism-modulating potential. We have categorized and summarized reported data on changes in disease indicators and gut microbiota abundance following alcoholic and non-alcoholic beer consumption. The positive effects of bioactive substances in beer in cancer prevention, reduction of cardiovascular events, and modulation of metabolic syndrome make it one of the candidates for microecological modulators.
作为一种历史悠久的发酵饮料，啤酒富含多种必需氨基酸、维生素、微量元素和生物活性物质，这些物质参与调节人体的多种生理功能。啤酒麦芽和啤酒花中的多酚也是重要的活性化合物，它们与肠道微生物群双向相互作用。本综述总结了啤酒中的多酚、纤维和其他有益成分被肠道微生物群发酵分解以启动黏膜免疫屏障并从而参与免疫调节的机制。啤酒降解产物具有抗炎、抗凝、抗氧化和调节糖脂代谢的潜力。我们对饮用酒精啤酒和非酒精啤酒后疾病指标变化及肠道微生物群丰度的报道数据进行了分类和总结。啤酒中生物活性物质在预防癌症、减少心血管事件和调节代谢综合征方面的积极作用使其成为微生态调节剂的候选者之一。
