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儿童期肺炎球菌感染:46名儿童肺炎球菌菌株的血清分型

Pneumococcal infections during childhood: serotyping of pneumococcal strains from forty-six children.

作者信息

Spencker F B, Handrick W, Fleurette J, Springer W, Rieske K, Bennek J

出版信息

Acta Paediatr Hung. 1986;27(2):97-105.

PMID:3756017
Abstract

The results of serotyping of forty-six strains of pneumococci isolated from children aged 3/12 to 14 9/12 years and diagnosed as having pneumonia, meningitis, primary peritonitis, otitis media, lymphadenitis, osteomyelitis, bacteraemia and conjunctivitis are presented. The results of serotyping and the frequency distribution of the detected serotypes were compared to the particular diagnoses established and the age at which the subjects involved had become ill. Questions of epidemiology and possibilities of immunoprophylaxis are discussed. Finally, the occurrence of pneumococci that are resistant to antibiotic agents are discussed since an isolated strain was found to show reduced susceptibility to penicillin G.

摘要

本文呈现了从3/12岁至14 9/12岁被诊断患有肺炎、脑膜炎、原发性腹膜炎、中耳炎、淋巴结炎、骨髓炎、菌血症和结膜炎的儿童中分离出的46株肺炎球菌的血清分型结果。将血清分型结果及检测到的血清型频率分布与所确定的具体诊断以及患病儿童的年龄进行了比较。讨论了流行病学问题和免疫预防的可能性。最后,由于发现一株分离菌株对青霉素G的敏感性降低,因此讨论了对抗生素耐药的肺炎球菌的出现情况。

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