以家族性高胆固醇血症为例，说明通过DNA技术早期诊断冠状动脉疾病风险。 - Suppr

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超能文献

Familial hypercholesterolaemia as an example of early diagnosis of coronary artery disease risk by DNA techniques.

作者信息

Humphries S E

出版信息

Br Heart J. 1986 Sep;56(3):201-5. doi: 10.1136/hrt.56.3.201.

DOI:10.1136/hrt.56.3.201

PMID:3756037

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1236843/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0934/1236843/3ffe24699b91/brheartj00105-0006-a.jpg

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本文引用的文献

Inheritance of mitral valve prolapse: effect of age and sex on gene expression.二尖瓣脱垂的遗传：年龄和性别对基因表达的影响。

Ann Intern Med. 1982 Dec;97(6):826-32. doi: 10.7326/0003-4819-97-6-826.

Hypercoagulability and coronary artery disease.

Br Heart J. 1984 Dec;52(6):614-6. doi: 10.1136/hrt.52.6.614.

Apoproteins: determinants of lipoprotein metabolism and indices of coronary risk.载脂蛋白：脂蛋白代谢的决定因素及冠心病风险指标

Br Heart J. 1984 Jun;51(6):585-8. doi: 10.1136/hrt.51.6.585.

Lipoprotein metabolism in the macrophage: implications for cholesterol deposition in atherosclerosis.巨噬细胞中的脂蛋白代谢：对动脉粥样硬化中胆固醇沉积的影响

Annu Rev Biochem. 1983;52:223-61. doi: 10.1146/annurev.bi.52.070183.001255.

The LDL receptor locus in familial hypercholesterolemia: multiple mutations disrupt transport and processing of a membrane receptor.家族性高胆固醇血症中的低密度脂蛋白受体基因座：多种突变破坏膜受体的转运和加工。

Cell. 1983 Mar;32(3):941-51. doi: 10.1016/0092-8674(83)90079-x.

Haemostatic function and cardiovascular death: early results of a prospective study.止血功能与心血管死亡：一项前瞻性研究的早期结果

Lancet. 1980 May 17;1(8177):1050-4. doi: 10.1016/s0140-6736(80)91498-1.

Plasma lipoproteins: apolipoprotein structure and function.血浆脂蛋白：载脂蛋白的结构与功能

J Lipid Res. 1984 Dec 1;25(12):1277-94.

The human LDL receptor: a cysteine-rich protein with multiple Alu sequences in its mRNA.人类低密度脂蛋白受体：一种在其信使核糖核酸中含有多个Alu序列的富含半胱氨酸的蛋白质。

Cell. 1984 Nov;39(1):27-38. doi: 10.1016/0092-8674(84)90188-0.

Probability of middle-aged men developing coronary heart disease in five years.中年男性在五年内患冠心病的概率。

Circulation. 1972 Apr;45(4):815-28. doi: 10.1161/01.cir.45.4.815.

Mutation in LDL receptor: Alu-Alu recombination deletes exons encoding transmembrane and cytoplasmic domains.低密度脂蛋白受体突变：Alu-Alu重组删除了编码跨膜和细胞质结构域的外显子。

Science. 1985 Jan 11;227(4683):140-6. doi: 10.1126/science.3155573.

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