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从全飞秒激光微小切口基质透镜切除术(SMILE)获取的透明角膜基质透镜作为游离移植物治疗原发性翼状胬肉的初步研究。

Transparent intrastromal corneal lenticule obtained from SMILE surgery as a free graft for the treatment of primary pterygium: A pilot study.

作者信息

Mutlu Said Nafiz, Evereklioglu Cem, Najafi Javid, Arda Hatice

机构信息

Maya Eye Hospital, Kayseri, Türkiye.

Department of Ophthalmology, Division of Cataract and Refractive Surgery, Erciyes University Medical Faculty, Kayseri, Türkiye.

出版信息

Am J Ophthalmol Case Rep. 2023 Jul 24;32:101897. doi: 10.1016/j.ajoc.2023.101897. eCollection 2023 Dec.

DOI:10.1016/j.ajoc.2023.101897
PMID:37560555
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10407624/
Abstract

PURPOSE

To report our initial experience in patients with primary pterygium surgery who had a transparent intrastromal corneal lenticule as a free graft obtained during small incision lenticule extraction (SMILE) surgery.

OBSERVATIONS

This study enrolled five eyes of 5 patients with pterygium who were surgically treated with single or double free lenticule that was sutured to the defective area of the nasal corneosclera immediately following pterygium excision. All cases with pterygium were primary, and topical mitomycin C was not used at the time of surgery. The mean age of the patients was 51.0 years and 2 of the 5 eyes belonged to male subjects. The patients were followed up for an average of six months. During the follow-up period, the lenticule grafts demonstrated no sign of rejection and were intact in all cases. All patients recovered well with no complications or recurrences at six months postoperatively.

CONCLUSIONS AND IMPORTANCE

This report suggests that transparent corneal lenticules obtained during SMILE laser surgery may be used as an alternative novel graft source for the surgical treatment of patients with primary pterygium. It appears to be a safe, easy, cost- and time-effective reliable method.

摘要

目的

报告我们在原发性翼状胬肉手术患者中的初步经验,这些患者在小切口基质透镜切除术(SMILE)手术中获得了透明的基质内角膜透镜作为游离移植物。

观察结果

本研究纳入了5例翼状胬肉患者的5只眼,这些患者接受了单或双游离透镜手术治疗,在翼状胬肉切除后立即将其缝合至鼻侧角膜巩膜缺损区域。所有翼状胬肉病例均为原发性,手术时未使用局部丝裂霉素C。患者的平均年龄为51.0岁,5只眼中有2只属于男性受试者。患者平均随访6个月。在随访期间,透镜移植物均未出现排斥迹象,所有病例均保持完整。所有患者恢复良好,术后6个月无并发症或复发。

结论与意义

本报告表明,SMILE激光手术中获得的透明角膜透镜可作为原发性翼状胬肉患者手术治疗的一种新型替代移植物来源。它似乎是一种安全、简便、经济且省时的可靠方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d11b/10407624/d0b2b623d884/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d11b/10407624/fdb92cd4bc85/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d11b/10407624/d0b2b623d884/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d11b/10407624/fdb92cd4bc85/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d11b/10407624/d0b2b623d884/gr2.jpg

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Int Ophthalmol. 2023 Jul;43(7):2521-2532. doi: 10.1007/s10792-023-02652-y. Epub 2023 Mar 4.
2
Cryopreserved Amniotic Membrane Using the TissueTuck Technique: A Sutureless Approach for Pterygium Surgery.采用 TissueTuck 技术冷冻保存羊膜:翼状胬肉手术的无缝线方法。
Cornea. 2023 Feb 1;42(2):181-185. doi: 10.1097/ICO.0000000000003111. Epub 2022 Sep 16.
3
Surgical Techniques and Adjuvants for the Management of Pterygium.
翼状胬肉治疗的手术技术与辅助治疗手段
Eye Contact Lens. 2022 Jan 1;48(1):3-13. doi: 10.1097/ICL.0000000000000849.
4
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Evaluation of change in pterygium induced keratometric astigmatism in patients following pterygium excision with autologous graft surgery.评价翼状胬肉切除联合自体移植物手术对翼状胬肉患者角膜散光的影响。
Nepal J Ophthalmol. 2020 Jul;12(24):191-200. doi: 10.3126/nepjoph.v12i2.28287.
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