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新型冠状病毒肺炎感染背景下的腹主动脉闭塞:文献综述与病例报告

Abdominal aortic occlusion in the setting of Covid 19 infection: literature review and a case report.

作者信息

Kimyaghalam Ali, Khan Shahkar, Bonilla Harrison, Singh Kuldeep

机构信息

Staten Island University Hospital, Staten Island, NY, USA.

出版信息

J Surg Case Rep. 2023 Aug 8;2023(8):rjad400. doi: 10.1093/jscr/rjad400. eCollection 2023 Aug.

DOI:10.1093/jscr/rjad400
PMID:37560608
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10409592/
Abstract

This case report and literature review aimed to evaluate the incidence and characteristics of abdominal aortic thrombosis in patients with COVID-19. A case report was presented of a 52-y-old male with past medical history significant only for hypertension who presented with lower extremity claudication 5 months after a mild COVID-19 infection. On imaging, he had an isolated aortic thrombus and underwent successful thrombectomy. To prevent devastating limb ischemia, we emphasize early evaluation of claudication symptoms in patients with COVID-19 or recent COVID-19 infection. A literature search was performed, which yielded nine articles relevant to concomitant COVID-19 infection and abdominal aortic occlusion (AAO). The results showed that the majority of patients presented with clinical features of acute limb ischemia, along with associated features of a hypercoagulable state. While the patient age range was wide, most patients were over the age of 50 y. The case report and literature review highlight the importance of recognizing the potential for AAO in patients with COVID-19, especially in those with risk factors such as advanced age or underlying medical conditions.

摘要

本病例报告及文献综述旨在评估新型冠状病毒肺炎(COVID-19)患者腹主动脉血栓形成的发生率及特征。报告了1例52岁男性病例,其既往病史仅有高血压,在轻度COVID-19感染5个月后出现下肢间歇性跛行。影像学检查显示其存在孤立性主动脉血栓,并成功接受了血栓切除术。为预防严重的肢体缺血,我们强调对COVID-19患者或近期感染过COVID-19的患者的间歇性跛行症状进行早期评估。进行了文献检索,共获得9篇与COVID-19合并感染及腹主动脉闭塞(AAO)相关的文章。结果显示,大多数患者表现为急性肢体缺血的临床特征,以及高凝状态的相关特征。虽然患者年龄范围较广,但大多数患者年龄超过50岁。该病例报告及文献综述强调了认识到COVID-19患者发生AAO的可能性的重要性,尤其是在那些具有高龄或基础疾病等危险因素的患者中。

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本文引用的文献

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Aortic thrombosis in a neonate with COVID-19-related fetal inflammatory response syndrome requiring amputation of the leg: a case report.COVID-19 相关胎儿炎症反应综合征导致新生儿主动脉血栓形成并需截肢:病例报告。
Paediatr Int Child Health. 2021 Aug;41(3):211-216. doi: 10.1080/20469047.2021.1968596. Epub 2021 Sep 7.
2
Acute limb ischemia in patients with COVID-19 pneumonia.新型冠状病毒肺炎患者的急性肢体缺血
J Vasc Surg. 2020 Dec;72(6):1864-1872. doi: 10.1016/j.jvs.2020.04.483. Epub 2020 Apr 29.
3
Acute aorto-iliac and mesenteric arterial thromboses as presenting features of COVID-19.
急性主-髂动脉和肠系膜动脉血栓形成作为新型冠状病毒肺炎的首发表现
Br J Haematol. 2020 Jun;189(6):1053-1054. doi: 10.1111/bjh.16760. Epub 2020 May 15.