Bashir Mohamed Ryan, Shehata Monica, Gorman William, AlShammari Abdullah, Buderi Silviu, Jordan Simon
Department of Thoracic Surgery, The Royal Brompton Hospital, London, UK.
University of Cambridge School of Clinical Medicine, Addenbrooke's Hospital, Cambridge, UK.
JRSM Open. 2023 Aug 7;14(8):20542704231188569. doi: 10.1177/20542704231188569. eCollection 2023 Aug.
Pulmonary epithelioid haemangioendothelioma (PEH) is a rare vascular neoplasm. The thoracic manifestation of this disorder is identified via three major imaging patterns, namely multiple primary nodules, diffuse infiltrative pleural thickening, and multiple pulmonary reticulonodular opacities. The commonest pattern of presentation is bilateral multiple nodules. Diagnosis is based on histopathological findings and verified by positive immunochemistry staining. Patients with PEH are usually asymptomatic. We report the case of a 51-year-old female who presented to our facility with a five-month history of cough, pleural nodularity, and pleural effusion. She underwent surgical washout with right pleural biopsies that showed a malignant epithelioid tumor with features of epithelioid haemangioendothelioma (EH). A CXR after treatment did not demonstrate a residual pleural effusion.
肺上皮样血管内皮瘤(PEH)是一种罕见的血管肿瘤。该疾病的胸部表现通过三种主要影像学模式得以识别,即多发原发性结节、弥漫性浸润性胸膜增厚以及多发肺网状结节状混浊。最常见的表现形式是双侧多发结节。诊断基于组织病理学发现,并通过阳性免疫化学染色加以验证。PEH患者通常无症状。我们报告一例51岁女性病例,她因咳嗽、胸膜结节和胸腔积液病史5个月前来我院就诊。她接受了手术冲洗及右胸膜活检,结果显示为具有上皮样血管内皮瘤(EH)特征的恶性上皮样肿瘤。治疗后的胸部X线检查未显示残留胸腔积液。