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早产儿视网膜病变:营养的作用

Retinopathy of Prematurity: The Role of Nutrition.

作者信息

Kim Esther S, Calkins Kara L, Chu Alison

出版信息

Pediatr Ann. 2023 Aug;52(8):e303-e308. doi: 10.3928/19382359-20230613-06. Epub 2023 Aug 1.

Abstract

Retinopathy of prematurity (ROP) is a leading cause of childhood blindness. ROP occurs in infants who are born very preterm. In ROP, retinal blood vessel development, which is prematurely arrested in preterm infants, is altered by perinatal exposures like oxygen and inflammation. Optimizing nutritional practices for preterm infants may mitigate the risk of ROP. In this article, we review the evidence that postnatal growth, hyperglycemia, polyunsaturated fatty acids, and breast milk provision may affect ROP risk. We also outline the current management strategies for ROP and describe the vision outcomes of children affected by ROP. .

摘要

早产儿视网膜病变(ROP)是导致儿童失明的主要原因。ROP发生在极早产的婴儿中。在ROP中,早产儿过早停止的视网膜血管发育会因围产期暴露如氧气和炎症而改变。优化早产儿的营养措施可能会降低ROP的风险。在本文中,我们综述了有关出生后生长、高血糖、多不饱和脂肪酸和母乳喂养可能影响ROP风险的证据。我们还概述了目前ROP的管理策略,并描述了受ROP影响儿童的视力结果。

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