Şener Taplak Ayşe, Erdem Emine
1 Department of Pediatric Nursing, Health School, Bozok University , Yozgat, Turkey .
2 Department of Pediatric Nursing, Faculty of Health Sciences, Erciyes University , Kayseri, Turkey .
Breastfeed Med. 2017 Jun;12:305-310. doi: 10.1089/bfm.2016.0122. Epub 2017 Apr 17.
This double-blind randomized controlled experimental study aimed to determine the effects of breast milk and sucrose in reducing pain in preterm infants during retinopathy of prematurity (ROP) examination.
This study was conducted with 60 preterm infants (breast milk group = 20, sucrose group = 20, and control/distilled water group = 20) meeting the inclusion criteria. The data were collected with the use of an Infant Evaluation Form, Procedure Monitoring Form, and Premature Infant Pain Profile (PIPP). The preterm infants were provided with 1 mL of breast milk, sucrose, and distilled water before the ROP examination. The pain level in preterm infants was measured by the PIPP 5 minutes before, during, and 5 minutes after the ROP examination. The ROP examinations were video recorded, and videos were evaluated by three observers blinded to the study.
No significant difference was determined between the three groups in terms of their postconceptional and postnatal ages, their body weights at birth and during the ROP examination. The PIPP scores of the preterm infants in the three groups were higher during the ROP examination and were not significantly different. The PIPP scores of the control group were significantly higher than those in the breast milk and sucrose groups after the ROP examination (p < 0.001). The preterm infants in the breast milk group recovered and returned to their initial values more quickly after the ROP examination than the infants in the sucrose group.
To reduce pain in preterm infants during ROP examination, breast milk is recommended.
这项双盲随机对照实验研究旨在确定母乳和蔗糖对降低早产儿视网膜病变（ROP）检查期间疼痛的影响。
本研究纳入了60名符合纳入标准的早产儿（母乳组 = 20名，蔗糖组 = 20名，对照组/蒸馏水组 = 20名）。使用婴儿评估表、操作监测表和早产儿疼痛量表（PIPP）收集数据。在ROP检查前，为早产儿提供1毫升母乳、蔗糖和蒸馏水。在ROP检查前5分钟、检查期间和检查后5分钟，通过PIPP测量早产儿的疼痛程度。ROP检查进行了视频记录，由三名对研究不知情的观察者对视频进行评估。
三组早产儿在孕龄和出生后年龄、出生时及ROP检查期间的体重方面无显著差异。三组早产儿在ROP检查期间的PIPP评分均较高，且无显著差异。ROP检查后，对照组的PIPP评分显著高于母乳组和蔗糖组（p < 0.001）。与蔗糖组相比，母乳组的早产儿在ROP检查后恢复更快，且回到初始值。
为降低早产儿ROP检查期间的疼痛，推荐使用母乳。
