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甲下角化棘皮瘤:一种罕见甲肿瘤的典型与非典型表现

Subungual Keratoacanthoma: Typical and Atypical Presentations of an Uncommon Nail Tumor.

作者信息

Figueroa-Ramos Grecia, Gatica-Torres Michelle, López-López Karla, Domínguez-Cherit Judith

机构信息

Department of Dermatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.

Tec Salud, Instituto Tecnológico y de Estudios Superiores de Monterrey, Mexico City, Mexico.

出版信息

Skin Appendage Disord. 2023 Aug;9(4):291-295. doi: 10.1159/000529724. Epub 2023 Apr 26.

DOI:10.1159/000529724
PMID:37564692
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10410088/
Abstract

INTRODUCTION

Keratoacanthoma (KA) is a group of tumors of epidermal origin with controversial nature. Subungual keratoacanthoma (SUKA) is a rare and destructive variant with more aggressive behavior. SUKA appears as a rapidly growing, painful tumor beneath the nail plate that rapidly progresses to a mass that can measure up to 2 cm. The toe location is unusual. The diagnosis must be made based on the correlation of clinical, radiological, and histopathological findings.

CASE PRESENTATION

We present two cases of patients diagnosed with SUKAs with different clinical presentations which ranged from very typical to uncommon one. Both cases were treated with simple excision without recurrences.

CONCLUSION

SUKA is a rare subungual tumor. Nail bed location represents a more difficult diagnostic challenge. SUKA should be suspected in the context of persistent and progressive pain on a finger or toe, once more frequent painful tumors have been ruled out.

摘要

引言

角化棘皮瘤(KA)是一组起源于表皮且性质存在争议的肿瘤。甲下角化棘皮瘤(SUKA)是一种罕见的、具有侵袭性的破坏性变种。SUKA表现为甲板下迅速生长的疼痛性肿瘤,可迅速发展为直径可达2厘米的肿块。其发生于趾部的情况较为少见。诊断必须基于临床、放射学和组织病理学检查结果的相关性。

病例报告

我们报告两例诊断为SUKA的患者,其临床表现各异,从非常典型到不常见。两例均采用简单切除术治疗,无复发。

结论

SUKA是一种罕见的甲下肿瘤。甲床部位的诊断更具挑战性。在排除了更常见的疼痛性肿瘤后,若手指或脚趾持续渐进性疼痛,应怀疑SUKA。

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本文引用的文献

1
Keratoacanthoma: Update on the Debate.角化棘皮瘤:争议更新。
Am J Dermatopathol. 2021 Apr 1;43(4):305-307. doi: 10.1097/DAD.0000000000001872.
2
Relationship between Human Papilloma Virus and Subungual Keratoacanthoma: Two Case Reports and the Outcomes of Surgical Treatment.人乳头瘤病毒与甲下角化棘皮瘤的关系:两例病例报告及手术治疗结果
Skin Appendage Disord. 2017 Jan;2(3-4):92-96. doi: 10.1159/000449064. Epub 2016 Sep 10.
3
Subungual Keratoacanthoma in a Patient With Yellow Nail Syndrome.黄甲综合征患者的甲下角化棘皮瘤
Dermatol Surg. 2016 Jul;42(7):900-2. doi: 10.1097/DSS.0000000000000734.
4
Subungual Keratoacanthoma.甲下角化棘皮瘤
Indian J Dermatol. 2015 Nov-Dec;60(6):623-4. doi: 10.4103/0019-5154.169148.
5
Natural course of keratoacanthoma and related lesions after partial biopsy: clinical analysis of 66 lesions.部分活检后角化棘皮瘤及相关病变的自然病程:66例病变的临床分析
J Dermatol. 2015 Apr;42(4):353-62. doi: 10.1111/1346-8138.12784. Epub 2015 Feb 10.
6
Nail tumors.指甲肿瘤。
Clin Dermatol. 2013 Sep-Oct;31(5):602-17. doi: 10.1016/j.clindermatol.2013.06.014.
7
Painful, rapidly growing tumor in the subungual area of the first digit of the right hand.右手食指指甲下区域出现疼痛且生长迅速的肿瘤。
Actas Dermosifiliogr. 2013 May;104(4):347-8. doi: 10.1016/j.adengl.2012.09.021. Epub 2013 Apr 6.
8
Recurrent distal digital keratoacanthoma of the periungual region treated with Mohs micrographic surgery.复发性甲周远端指节部角化棘皮瘤采用 Mohs 显微外科手术治疗。
Australas J Dermatol. 2012 Feb;53(1):e5-7. doi: 10.1111/j.1440-0960.2010.00692.x. Epub 2010 Sep 10.
9
[Subungual keratoacanthoma: the importance of distinguishing it from subungual squamous cell carcinoma].[甲下角化棘皮瘤:将其与甲下鳞状细胞癌相鉴别诊断的重要性]
Actas Dermosifiliogr. 2012 Jul-Aug;103(6):549-51. doi: 10.1016/j.ad.2011.08.012. Epub 2012 Jan 25.
10
[Subungual keratoacanthoma].[甲下角化棘皮瘤]
Ann Dermatol Venereol. 2012 Jan;139(1):68-72. doi: 10.1016/j.annder.2011.09.011. Epub 2011 Oct 27.