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复发性皮肤利什曼病的临床特征与诊断

Clinical Profile and Diagnosis of Recurrent Cutaneous Leishmaniasis.

作者信息

Arruda Sérgio, Agra-Duarte Gabriela, Lago Jamile, Oliveira Lívia, Zacarias Evelyn, Carvalho Lucas P, Machado Paulo R L, de Oliveira Camila I, Carvalho Edgar M

机构信息

Instituto Gonçalo Moniz, Fiocruz, Salvador, Brasil.

Department of Pathology, Universidade Estadual da Bahia, Salvador, Brasil.

出版信息

Open Forum Infect Dis. 2023 Jul 22;10(8):ofad387. doi: 10.1093/ofid/ofad387. eCollection 2023 Aug.

DOI:10.1093/ofid/ofad387
PMID:37564745
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10411034/
Abstract

This case-control study compared the clinical profile, parasite load, polymerase chain reaction positivity, and response to therapy in patients with recurrent cutaneous leishmaniasis (RCL) with primary cutaneous leishmaniasis (CL). The RCL patients had milder diseases with lower parasite loads, a lower number of lesions, and more self-healing diseases than primary CL patients.

摘要

这项病例对照研究比较了复发性皮肤利什曼病（RCL）患者与原发性皮肤利什曼病（CL）患者的临床特征、寄生虫负荷、聚合酶链反应阳性率以及对治疗的反应。与原发性CL患者相比，RCL患者的疾病症状较轻，寄生虫负荷较低，病损数量较少，自愈性疾病较多。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92f2/10411034/371f8fb4a5b2/ofad387f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92f2/10411034/371f8fb4a5b2/ofad387f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92f2/10411034/371f8fb4a5b2/ofad387f1.jpg

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J Infect Public Health. 2022 Nov;15(11):1175-1179. doi: 10.1016/j.jiph.2022.09.010. Epub 2022 Sep 27.
2
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PLoS Negl Trop Dis. 2021 Jan 28;15(1):e0009089. doi: 10.1371/journal.pntd.0009089. eCollection 2021 Jan.
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Tissue Damage in Human Cutaneous Leishmaniasis: Correlations Between Inflammatory Cells and Molecule Expression.人类皮肤利什曼病中的组织损伤：炎症细胞与分子表达之间的相关性
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