Islam Aliya, Niazi Shaharyar K
Public Health, SurgiMed Hospital, Islamabad, PAK.
Cureus. 2023 Jul 10;15(7):e41629. doi: 10.7759/cureus.41629. eCollection 2023 Jul.
Background Subclinical hypothyroidism is a common endocrine disorder during pregnancy, associated with adverse maternal and fetal outcomes. This study aimed to evaluate the frequency of subclinical hypothyroidism among pregnant women who presented to our hospital between 2020 and 2022. Methods A retrospective chart review was conducted on 589 pregnant women using convenience sampling. Only women who underwent thyroid function testing and had no known thyroid disease were included. Data on age, weight status, history of miscarriage, history of infertility, menstrual cycle regularity, thyroid function, and symptoms of thyroid diseases were collected. Descriptive statistics were used to analyze the data. Results The mean age of the participants was 24.8 ± 3.7 years. Among the participants, 270 (45.9%) had a normal weight, 199 (33.8%) were overweight, and 120 (20.4%) were obese. A history of miscarriage was reported by 69 women (11.7%) while 37 women (6.3%) had a history of infertility. The menstrual cycle was regular in 499 women (84.7%) and irregular in 90 women (15.3%). The results showed that 517 (87.7%) women were euthyroid, 47 (7.9%) had hypothyroidism, and 25 (4.2%) had hyperthyroidism. Of the 47 patients with hypothyroidism, 32 (68.08%) had subclinical hypothyroidism and 15 (31.91%) had overt hypothyroidism. Conclusion This study highlights the frequency of subclinical hypothyroidism among pregnant women. The findings underscore the importance of thyroid function testing during pregnancy.
背景 亚临床甲状腺功能减退是孕期常见的内分泌疾病，与不良母婴结局相关。本研究旨在评估2020年至2022年期间到我院就诊的孕妇中亚临床甲状腺功能减退的发生率。方法 采用便利抽样法对589名孕妇进行回顾性病历审查。仅纳入接受过甲状腺功能检测且无已知甲状腺疾病的女性。收集了年龄、体重状况、流产史、不孕史、月经周期规律情况、甲状腺功能及甲状腺疾病症状等数据。采用描述性统计方法分析数据。结果 参与者的平均年龄为24.8±3.7岁。在参与者中，270人（45.9%）体重正常，199人（33.8%）超重，120人（20.4%）肥胖。69名女性（11.7%）报告有流产史，37名女性（6.3%）有不孕史。499名女性（84.7%）月经周期规律，90名女性（15.3%）月经周期不规律。结果显示，517名（87.7%）女性甲状腺功能正常，47名（7.9%）患有甲状腺功能减退，25名（4.2%）患有甲状腺功能亢进。在47例甲状腺功能减退患者中，32例（68.08%）为亚临床甲状腺功能减退，15例（31.91%）为显性甲状腺功能减退。结论 本研究突出了孕妇中亚临床甲状腺功能减退的发生率。研究结果强调了孕期甲状腺功能检测的重要性。
