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乳腺胆固醇肉芽肿酷似癌症:病例报告及文献复习。

Cholesterol Granuloma of the Breast Mimicking Cancer: A Case Report and Review of the Literature.

机构信息

Mohamed Taher Maamouri University Hospital, Nabeul, Tunisia.

出版信息

J Investig Med High Impact Case Rep. 2023 Jan-Dec;11:23247096231193275. doi: 10.1177/23247096231193275.

DOI:10.1177/23247096231193275
PMID:37565689
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10422883/
Abstract

Cholesterol granuloma of the breast is an infrequent benign lesion with clinical and radiological findings suggestive of cancer. Herein, we present the case of a 52-year-old woman with no significant past medical history, who presented to the outpatient department for her routine breast screening. Physical examination revealed a painless palpable nodule in the upper external quadrant of the left breast, measuring 0.7 cm. On imaging, the mass met the criteria for Breast Imaging Reporting and Data System (BI-RADS) category 4B. Subsequently, a core needle biopsy of the mass was performed. Despite the alarming radiologic features, microscopic findings were consistent with breast cholesterol granuloma.

摘要

乳房胆固醇肉芽肿是一种罕见的良性病变,其临床表现和影像学表现提示为癌症。在此,我们报告了一例 52 岁女性的病例,她无明显的既往病史,因常规乳房筛查到门诊就诊。体格检查发现左乳房外上象限可触及一无痛可触及的结节,大小为 0.7 厘米。影像学检查显示肿块符合乳腺影像报告和数据系统 (BI-RADS) 4B 类标准。随后对肿块进行了空心针活检。尽管影像学特征令人担忧,但显微镜下的发现与乳腺胆固醇肉芽肿一致。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/678c/10422883/a95b1229fc1a/10.1177_23247096231193275-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/678c/10422883/a95b1229fc1a/10.1177_23247096231193275-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/678c/10422883/a95b1229fc1a/10.1177_23247096231193275-fig1.jpg

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本文引用的文献

1
Multiple cholesterol granulomas of the breast: A case report and review of the literature.乳房多发胆固醇肉芽肿:病例报告及文献复习。
Medicine (Baltimore). 2023 Feb 22;102(8):e33084. doi: 10.1097/MD.0000000000033084.
2
Increasing Size of Cholesterol Granuloma of the Breast in the Vicinity of a Previous Breast Biopsy: Imaging Features and Review of the Literature.既往乳腺活检部位附近乳腺胆固醇肉芽肿增大:影像学特征及文献复习
Am J Case Rep. 2019 Mar 21;20:370-376. doi: 10.12659/AJCR.914282.
3
T1-Weighted Dynamic Contrast-Enhanced Magnetic Resonance Imaging (DCE-MRI) to Distinguish Between Concurrent Cholesterol Granuloma and Invasive Ductal Carcinoma of the Breast: A Case Report.
利用T1加权动态对比增强磁共振成像(DCE-MRI)鉴别乳腺同时存在的胆固醇肉芽肿与浸润性导管癌:病例报告
Am J Case Rep. 2018 May 23;19:593-598. doi: 10.12659/AJCR.909161.
4
Sonographic appearance of a cholesterol granuloma mimicking breast cancer.超声表现为酷似乳腺癌的胆固醇肉芽肿。
J Clin Ultrasound. 2017 Nov 12;45(9):608-611. doi: 10.1002/jcu.22453. Epub 2017 Feb 21.
5
Cholesterol Granuloma: An Unusual and Benign Cause of Focal FDG Uptake in the Breast Detected on PET/CT.胆固醇肉芽肿:PET/CT 探测到的乳腺局灶性 FDG 摄取的一种不常见良性原因。
Clin Nucl Med. 2015 Nov;40(11):e511-3. doi: 10.1097/RLU.0000000000000924.
6
Breast cholesterol granuloma: a report of two cases with discussion on potential pathogenesis.
Pathologica. 2013 Dec;105(6):349-52.
7
Cholesterol granuloma of the breast mimicking malignancy.酷似恶性肿瘤的乳腺胆固醇肉芽肿
BMJ Case Rep. 2013 Aug 7;2013:bcr2013200108. doi: 10.1136/bcr-2013-200108.
8
The unusual ultrasound features of a breast cholesterol granuloma manifesting as an intracystic mass: case report and literature review.表现为囊内肿块的乳腺胆固醇肉芽肿的超声特征:病例报告及文献复习。
Korean J Radiol. 2013 Mar-Apr;14(2):179-82. doi: 10.3348/kjr.2013.14.2.179. Epub 2013 Feb 22.
9
Cholesterol granuloma of the breast with unusual ossification features (osseous metaplasia).具有异常骨化特征(骨化生)的乳腺胆固醇肉芽肿
Pathol Res Pract. 2008;204(5):353-6. doi: 10.1016/j.prp.2007.12.004. Epub 2008 Feb 13.
10
A case of breast cholesterol granuloma accompanied by cancer.一例伴有癌症的乳腺胆固醇肉芽肿。
Breast Cancer. 2004;11(2):210-3. doi: 10.1007/BF02968304.