Genest J
Can J Physiol Pharmacol. 1986 Jun;64(6):836-9. doi: 10.1139/y86-144.
A succinct overview of the nutritional management of hypertension, past, present, and future is presented. Prior to 1945, the low sodium diet and the rice-fruit diet were shown to be effective in reducing the blood pressure to normal levels in 35-40% of hypertensive patients. Between 1945 and the present, many studies were made on the effects of alcohol, water hardness, obesity, moderate restriction of sodium with increased potassium intake, increased dietary calcium, low animal and high unsaturated fat intake, and increased amounts of fiber in the diet. Criticisms are made of the very small magnitude, even if statistically significant, of blood pressure decreases and the too-short control periods in many instances, and also concerning the assumption of use of 24-h urinary sodium as an accurate index of the sodium intake, and of urinary creatinine as a physiological reference standard against the excretion of sodium. The author mentions, for possible future research, long-term studies of the effects of diets moderately restricted in sodium and high in potassium, of reducing weight and increasing physical activity in obese hypertensives, and of low animal and high polyunsaturated fat diets in patients with mild essential hypertension.
本文简要概述了高血压营养管理的过去、现在和未来。1945年以前,低钠饮食和米果饮食被证明能使35%至40%的高血压患者血压降至正常水平。1945年至今,人们对酒精、水硬度、肥胖、适度限制钠摄入并增加钾摄入、增加膳食钙、低动物脂肪和高不饱和脂肪摄入以及增加膳食纤维等因素的影响进行了许多研究。有人批评这些研究中血压下降幅度非常小(即使具有统计学意义),且在许多情况下控制期过短,还批评了将24小时尿钠作为钠摄入量的准确指标以及将尿肌酐作为钠排泄生理参考标准的假设。作者提到,未来可能的研究方向包括对适度限钠高钾饮食的长期影响、肥胖高血压患者减重和增加体力活动的长期影响以及轻度原发性高血压患者低动物脂肪和高多不饱和脂肪饮食的长期影响的研究。