Uridine: as sweet as sugar for some cells?
作者信息
Ward Matthew H, Nwosu Zeribe C, Lyssiotis Costas A
机构信息
Department of Chemistry, Washington University in St. Louis, St. Louis, MO, USA.
Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
出版信息
Cell Res. 2023 Dec;33(12):898-899. doi: 10.1038/s41422-023-00860-w.
Abstract
摘要
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Salvage of ribose from uridine or RNA supports glycolysis in nutrient-limited conditions.从尿苷或 RNA 中回收核糖可支持营养有限条件下的糖酵解。
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Circulating uridine dynamically and adaptively regulates food intake in humans.循环尿苷动态且适应性地调节人体的食物摄入。
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Inosine is an alternative carbon source for CD8-T-cell function under glucose restriction.肌苷是葡萄糖限制下 CD8-T 细胞功能的替代碳源。
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