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磁控胶囊内镜在老年患者中的应用性能。

Magnetic-controlled capsule endoscopy performance in aging patients.

机构信息

Department of Geriatrics, Peking University First Hospital, No. 8 Xishiku St., Xicheng District, Beijing, 100034, China.

出版信息

BMC Gastroenterol. 2023 Aug 11;23(1):277. doi: 10.1186/s12876-023-02914-0.

DOI:10.1186/s12876-023-02914-0
PMID:37568133
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10422704/
Abstract

BACKGROUND

The increasing elderly population and wide use of magnetic capsule endoscopy (MCE) have led to more attention to elderly patients.

AIM

The aim of this study was to assess the performance (including transit time, cleanliness score, positive findings and safety) of MCE in aging patients (≥ 60 years), especially patients over 80 years old.

METHODS

Consecutive patients of ≥ 60 years undergoing MCE at our center from August 2017 to August 2022 were classified into the oldest (≥ 80 years) and the older (60-79 years) groups. Esophageal transit time (ETT), gastric examination time (GET), small bowel transit time (SITT), and the quality of gastric preparation were compared. Information on examination indications, subjective discomforts, adverse events, and MCE outcomes were compared.

RESULTS

Of 293 enrolled patients, 128 patients were in the oldest group and 165 patients were in the older group. ETT and GET were longer in the oldest group, whereas SITT was slightly longer in the oldest patients. Visualization scores were significantly lower in the body and antrum in the oldest patients. The total visualization score was lower in the older group compared with the oldest group; however, the difference was not significant. Cleanliness scores at the fundus and antrum and total cleanliness scores were lower in the oldest patients compared with the older patients. Positive findings and ulcers and erosions in the small intestine were more common in the oldest group. One patient had nausea during the gastric examination. Capsule retention in the cecum occurred in one case.

CONCLUSION

MCE was feasible and safe for aging patients. ETT and GET were markedly longer and gastric cleanliness and visualization were worse, while overall small intestine-positive findings were higher in the oldest patients compared with the older patients.

摘要

背景

随着老年人口的增加和磁控胶囊内镜(MCE)的广泛应用,人们越来越关注老年患者。

目的

本研究旨在评估 MCE 在老年患者(≥60 岁)中的表现(包括传输时间、清洁评分、阳性发现和安全性),特别是 80 岁以上的患者。

方法

连续纳入 2017 年 8 月至 2022 年 8 月在本中心行 MCE 的≥60 岁患者,分为最年长(≥80 岁)和年长(60-79 岁)两组。比较食管传输时间(ETT)、胃检查时间(GET)、小肠传输时间(SITT)和胃准备质量。比较检查指征、主观不适、不良事件和 MCE 结果。

结果

共纳入 293 例患者,其中 128 例在最年长组,165 例在年长组。最年长组的 ETT 和 GET 较长,而最年长组的 SITT 稍长。最年长患者胃体和胃窦的可视评分明显较低。年长组的总可视评分较最年长组低,但差异无统计学意义。最年长患者胃底和胃窦的清洁评分以及总清洁评分均低于年长组。最年长组的阳性发现和小肠溃疡及糜烂更为常见。1 例患者在胃检查时出现恶心,1 例患者胶囊滞留于盲肠。

结论

MCE 对老年患者是可行且安全的。与年长患者相比,最年长患者的 ETT 和 GET 明显较长,胃清洁度和可视性较差,而小肠总阳性发现较高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3494/10422704/81b7e36afea3/12876_2023_2914_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3494/10422704/e3c1831b9c28/12876_2023_2914_Figa_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3494/10422704/002a407d8434/12876_2023_2914_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3494/10422704/4e03f18685aa/12876_2023_2914_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3494/10422704/33da5ba2301a/12876_2023_2914_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3494/10422704/81b7e36afea3/12876_2023_2914_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3494/10422704/e3c1831b9c28/12876_2023_2914_Figa_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3494/10422704/002a407d8434/12876_2023_2914_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3494/10422704/4e03f18685aa/12876_2023_2914_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3494/10422704/33da5ba2301a/12876_2023_2914_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3494/10422704/81b7e36afea3/12876_2023_2914_Fig6_HTML.jpg

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Effect of Different Modalities of Purgative Preparation on the Diagnostic Yield of Small Bowel Capsule for the Exploration of Suspected Small Bowel Bleeding: A Multicenter Randomized Controlled Trial.不同导泻准备方式对疑似小肠出血小肠胶囊内镜检查诊断效果的影响:一项多中心随机对照试验。
Am J Gastroenterol. 2022 Feb 1;117(2):327-335. doi: 10.14309/ajg.0000000000001597.
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Value of the diving method for capsule endoscopy in the examination of small-intestinal disease: a prospective randomized controlled trial.
潜水法胶囊内镜检查在小肠疾病中的价值:一项前瞻性随机对照试验。
Gastrointest Endosc. 2021 Oct;94(4):795-802.e1. doi: 10.1016/j.gie.2021.04.018. Epub 2021 Apr 28.
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Detachable string magnetically controlled capsule endoscopy for complete observation of the upper gastrointestinal tract.可拆卸式磁控胶囊内镜对上消化道的全面观察。
Eur J Gastroenterol Hepatol. 2021 Apr 1;33(4):508-513. doi: 10.1097/MEG.0000000000001939.
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