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慢性阻塞性肺疾病在实际临床实践中健康状况、呼吸道症状和呼吸困难的概念独立性

The Conceptual Independence of Health Status, Respiratory Symptoms and Dyspnea in Chronic Obstructive Pulmonary Disease in Real Clinical Practice.

作者信息

Nishimura Koichi, Kusunose Masaaki, Mori Mio, Shibayama Ayumi, Nakayasu Kazuhito

机构信息

Visiting Researcher, National Center for Geriatrics and Gerontology, 7-430, Morioka-cho, Obu 474-8511, Japan.

Clinic Nishimura, 4-3. Kohigashi, Kuri-cho, Ayabe 623-0222, Japan.

出版信息

Diagnostics (Basel). 2023 Jul 27;13(15):2492. doi: 10.3390/diagnostics13152492.

DOI:10.3390/diagnostics13152492
PMID:37568855
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10417120/
Abstract

The hypothesis that health status is the highest ranking concept, followed by respiratory symptoms and dyspnea as the lowest ranking concepts in subjects with chronic obstructive pulmonary disease (COPD) was tested in a real clinical setting with 157 subjects with stable COPD. Spearman's rank correlation coefficients for scores of health status using the COPD Assessment Test (CAT), respiratory symptoms using the COPD Evaluating Respiratory Symptoms (E-RS) and dyspnea using Dyspnea-12 (D-12) between any two were 0.6 to 0.7. Upon categorizing the patients as "abnormal" or "normal" according to the threshold, it was found that 30 patients (19.1%) had dyspnea, respiratory symptoms and impaired health status. Dyspnea was considered an important part of respiratory symptoms, though seven patients had dyspnea but no respiratory symptoms. There were 10 patients who had respiratory symptoms without dyspnea but without health status problems. Furthermore, there were six patients who had both dyspnea and respiratory symptoms but whose health status was classified as fine. Thus, the hypothesis was correct in approximately 85% of cases.

摘要

在157名稳定期慢性阻塞性肺疾病(COPD)患者的真实临床环境中,对“健康状况是最高等级概念,其次是呼吸症状和呼吸困难,后者是COPD患者中最低等级概念”这一假设进行了检验。使用慢性阻塞性肺疾病评估测试(CAT)评估健康状况得分、使用慢性阻塞性肺疾病呼吸症状评估量表(E-RS)评估呼吸症状得分以及使用呼吸困难量表12(D-12)评估呼吸困难得分,任意两者之间的斯皮尔曼等级相关系数为0.6至0.7。根据阈值将患者分为“异常”或“正常”,发现30名患者(19.1%)存在呼吸困难、呼吸症状和健康状况受损。呼吸困难被认为是呼吸症状的重要组成部分,尽管有7名患者有呼吸困难但无呼吸症状。有10名患者有呼吸症状但无呼吸困难且健康状况无问题。此外,有6名患者既有呼吸困难又有呼吸症状,但其健康状况被分类为良好。因此,该假设在大约85%的病例中是正确的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b281/10417120/92d36e41e69c/diagnostics-13-02492-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b281/10417120/3e84e3dad641/diagnostics-13-02492-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b281/10417120/5a716fa52c5e/diagnostics-13-02492-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b281/10417120/92d36e41e69c/diagnostics-13-02492-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b281/10417120/3e84e3dad641/diagnostics-13-02492-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b281/10417120/5a716fa52c5e/diagnostics-13-02492-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b281/10417120/92d36e41e69c/diagnostics-13-02492-g003.jpg

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