前列腺癌前哨淋巴结活检：诊断性能、肿瘤学结局、安全性及可行性概述
Sentinel Lymph Node Biopsy in Prostate Cancer: An Overview of Diagnostic Performance, Oncological Outcomes, Safety, and Feasibility.
作者信息
Rossin Giulio, Zorzi Federico, De Pablos-Rodríguez Pedro, Biasatti Arianna, Marenco Josè, Ongaro Luca, Perotti Alessandro, Tulone Gabriele, Traunero Fabio, Piasentin Andrea, Gomez-Ferrer Alvaro, Zucchi Alessandro, Trombetta Carlo, Simonato Alchiede, Rubio-Briones José, Bartoletti Riccardo, Ramírez-Backhaus Miguel, Claps Francesco
机构信息
Urological Clinic, Department of Medicine, Surgery and Health Sciences, University of Trieste, Strada di Fiume, 447, 34149 Trieste, Italy.
Department of Urology, Valencian Oncology Institute Foundation, FIVO, 46009 Valencia, Spain.
出版信息
Diagnostics (Basel). 2023 Jul 31;13(15):2543. doi: 10.3390/diagnostics13152543.
Abstract
Sentinel node biopsy (SNB) for prostate cancer (PCa) represents an innovative technique aimed at improving nodal staging accuracy. The routinary adoption of this procedure in patients undergoing radical prostatectomy (RP) might be crucial to identify candidates who could effectively benefit from extensive pelvic lymph nodal dissection (ePLND). Despite some promising results, SNB for PCa is still considered experimental due to the lack of solid evidence and procedural standardization. In this regard, our narrative review aimed to analyze the most recent literature in this field, providing an overview of both the diagnostic accuracy measures and the oncological outcomes of SNB.
摘要
前列腺癌（PCa）的前哨淋巴结活检（SNB）是一项旨在提高淋巴结分期准确性的创新技术。在接受根治性前列腺切除术（RP）的患者中常规采用该手术对于识别可能从广泛盆腔淋巴结清扫术（ePLND）中有效获益的患者可能至关重要。尽管有一些令人鼓舞的结果，但由于缺乏确凿证据和程序标准化，PCa的SNB仍被视为实验性的。在这方面，我们的叙述性综述旨在分析该领域的最新文献，概述SNB的诊断准确性指标和肿瘤学结局。
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本文引用的文献
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Clin Genitourin Cancer. 2023 Dec;21(6):e461-e466.e1. doi: 10.1016/j.clgc.2023.05.010. Epub 2023 May 18.
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Eur Urol. 2023 Jul;84(1):65-85. doi: 10.1016/j.eururo.2023.03.014. Epub 2023 Apr 27.
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Eur J Nucl Med Mol Imaging. 2023 Jul;50(9):2861-2871. doi: 10.1007/s00259-023-06191-7. Epub 2023 Apr 10.
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