Bărbulescu Linda-Nicoleta, Rădulescu Virginia-Maria, Mogoantă Stelian-Ștefăniță, Bărbulescu Lucian-Florentin, Kamal Constantin, Radu Mirela, Cismaru Liana
Doctoral School, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Cabinet Medical Dr. Profir I. Mirela SRL, 200145 Craiova, Romania.
Diagnostics (Basel). 2023 Aug 1;13(15):2556. doi: 10.3390/diagnostics13152556.
This study aims to develop a scoring method that can be used by primary care physicians from remote areas or resource-limited settings to estimate the need for fecal occult blood testing (FOBT) as a first step in colorectal cancer screening. This method relies on several modifiable risk factors that can influence a positive FOBT, an indication of the presence of colorectal polyps, or even colorectal cancer. The scoring method considers, besides the age and gender of the patient, the body mass index (BMI), smoking status, and the diagnoses of diabetes mellitus (type 2 diabetes), dyslipidemia, and hypertension. It does not need any paraclinical exams, which is an advantage when access or material resources are limited. The retrospective study was spread over forty-three months, respectively, from October 2019 to April 2023, and included 112 patients. The score that we designed is a numerical value between 0 and 7. The values between 0 and 3 represent a smaller risk of a positive FOBT (9.68%), values 4 and 5 represent a medium risk (14.75%), while values 6 and 7 represent a greater risk (40%). Using this score, a physician can determine if a patient has a greater risk and recommend it to prioritize taking a FOB test.
本研究旨在开发一种评分方法,供偏远地区或资源有限环境中的基层医疗医生用于评估粪便潜血试验(FOBT)作为结直肠癌筛查第一步的必要性。该方法基于几个可改变的风险因素,这些因素可能影响FOBT呈阳性,提示存在结直肠息肉甚至结直肠癌。除患者的年龄和性别外,评分方法还考虑体重指数(BMI)、吸烟状况以及糖尿病(2型糖尿病)、血脂异常和高血压的诊断情况。它不需要任何辅助检查,在获取资源或物质资源有限时这是一个优势。这项回顾性研究分别跨越了2019年10月至2023年4月的43个月,纳入了112名患者。我们设计的评分是一个介于0到7之间的数值。0到3之间的值表示FOBT呈阳性的风险较小(9.68%),4和5的值表示中等风险(14.75%),而6和7的值表示风险较大(40%)。使用这个评分,医生可以确定患者是否有更大风险,并建议优先进行FOBT检测。