Zhang Shiyu, Zhang Junyong, Kim Yonghwan, Zhang Wangyang
School of Physical Education in Main Campus, Zhengzhou University, Zhengzhou 450001, China.
Department of Physical Education, Gangneung-Wonju National University, Gangneung 25457, Korea.
Healthcare (Basel). 2021 Oct 19;9(10):1400. doi: 10.3390/healthcare9101400.
Colorectal polyps are precursor lesions of colorectal cancer and are known to be associated with obesity, low physical activity, and unhealthy behavior. This cross-sectional study analyzed the prevalence of colorectal polyps based on cardiorespiratory fitness (CRF), muscle strength, and health behavior in older adults. Participants were asymptomatic and included 1024 men and 472 women aged 65-80 years who visited the health care center. Colonoscopy was performed under conscious sedation, and cardiorespiratory fitness was measured as the maximum oxygen uptake using gas analysis. Muscle strength was determined using isokinetic equipment, and physical activity, alcohol consumption, and smoking status were investigated using questionnaires. Waist circumference was measured at the thickest part of the middle of the abdomen. Logistic regression analysis was used to calculate the prevalence of colorectal polyps using odds ratios (ORs) based on the variables. The incidence of colorectal polyps was 65.2% in men and 48.5% in women. The ORs of colorectal polyps for obesity were 1.151 (95% confidence interval [CI], 1.010-2.291) and 1.178 (95% CI, 1.015-2.612) in men and women, respectively. The OR for colorectal polyps in male current smokers was 1.884. The ORs for low CRF were 1.985 and 1.841 in men and women, respectively, compared with high CRF. The prevalence of polyps increased with low muscle strength (men's OR 1.343 women's OR 1.440) and physical activity in both men (OR 1.693) and women (OR 1.861). In conclusion, lower CRF and muscle strength were associated with an increased prevalence of colorectal polyps in men and women. In both sexes, high waist circumference and low physical activity increased the prevalence of colorectal polyps.
结直肠息肉是结直肠癌的前驱病变，已知与肥胖、低体力活动和不健康行为有关。这项横断面研究分析了基于心肺适能（CRF）、肌肉力量和健康行为的老年人结直肠息肉患病率。参与者无症状，包括1024名年龄在65 - 80岁之间前往医疗保健中心就诊的男性和472名女性。在清醒镇静状态下进行结肠镜检查，使用气体分析将心肺适能测量为最大摄氧量。使用等速设备测定肌肉力量，并通过问卷调查调查体力活动、饮酒情况和吸烟状况。在腹部中部最粗处测量腰围。采用逻辑回归分析，根据变量使用比值比（OR）计算结直肠息肉的患病率。男性结直肠息肉的发病率为65.2%，女性为48.5%。男性和女性肥胖者患结直肠息肉的OR分别为1.151（95%置信区间[CI]，1.010 - 2.291）和1.178（95%CI，1.015 - 2.612）。男性当前吸烟者患结直肠息肉的OR为1.884。与高CRF相比，低CRF者患结直肠息肉的OR在男性和女性中分别为1.985和1.841。息肉患病率随肌肉力量降低（男性OR 1.343，女性OR 1.440）以及男性（OR 1.693）和女性（OR 1.861）的体力活动降低而增加。总之，较低的CRF和肌肉力量与男性和女性结直肠息肉患病率增加有关。在两性中，高腰围和低体力活动均增加了结直肠息肉的患病率。
