Garnica-Bohórquez Israel, Güiza-Argüello Viviana R, López-Gualdrón Clara I
Industrial Design Department, Universidad Industrial de Santander, Bucaramanga 680002, Colombia.
Metallurgical Engineering and Materials Science Department, Universidad Industrial de Santander, Bucaramanga 680002, Colombia.
Polymers (Basel). 2023 Aug 6;15(15):3317. doi: 10.3390/polym15153317.
To successfully implement additive manufacturing (AM) techniques for custom medical device (MD) production with low-cost resources, it is imperative to understand the effect of common and affordable sterilization processes, such as formaldehyde or steam sterilization, on pieces manufactured by AM. In this way, the performance of low-risk MDs, such as biomodels and surgical guides, could be assessed for complying with safety, precision, and MD delivery requirements. In this context, the aim of the present work was to evaluate the effect of formaldehyde and steam sterilization on the dimensional and mechanical stability of standard polylactic acid (PLA) test pieces produced by fused deposition modeling (FDM). To achieve this, PLA samples were sterilized according to the sterilization protocol of a public hospital in the city of Bucaramanga, Colombia. Significant changes regarding mechanical and dimensional properties were found as a function of manufacturing parameters. This research attempts to contribute to the development of affordable approaches for the fabrication of functional and customized medical devices through AM technologies, an issue of particular interest for low- and middle-income countries.
为了利用低成本资源成功实施增材制造（AM）技术来生产定制医疗设备（MD），必须了解常见且经济实惠的灭菌工艺（如甲醛或蒸汽灭菌）对通过增材制造生产的部件的影响。通过这种方式，可以评估生物模型和手术导板等低风险医疗设备的性能，以符合安全性、精度和医疗设备交付要求。在此背景下，本研究的目的是评估甲醛和蒸汽灭菌对通过熔融沉积建模（FDM）生产的标准聚乳酸（PLA）测试件的尺寸和机械稳定性的影响。为实现这一目标，根据哥伦比亚布卡拉曼加市一家公立医院的灭菌方案对PLA样品进行灭菌。发现机械性能和尺寸性能随制造参数发生了显著变化。本研究试图通过增材制造技术为开发经济实惠的功能性定制医疗设备制造方法做出贡献，这一问题对低收入和中等收入国家尤为重要。
