Sensing System Research Center, National Institute of Advanced Industrial Science and Technology (AIST), Central 5, 1-1-1 Higashi, Tsukuba 305-8565, Ibaraki, Japan.
Sensors (Basel). 2023 Jul 31;23(15):6830. doi: 10.3390/s23156830.
Various viral diseases can be widespread and cause severe disruption to global society. Highly sensitive virus detection methods are needed to take effective measures to prevent the spread of viral infection. This required the development of rapid virus detection technology to detect viruses at low concentrations, even in the biological fluid of patients in the early stages of the disease or environmental samples. This review describes an overview of various virus detection technologies and then refers to typical technologies such as beads-based assay, digital assay, and pore-based sensing, which are the three modern approaches to improve the performance of viral sensing in terms of speed and sensitivity.
各种病毒性疾病可能会广泛传播,并严重扰乱全球社会。需要高度敏感的病毒检测方法来采取有效措施防止病毒感染的传播。这需要开发快速病毒检测技术,以检测低浓度的病毒,甚至可以在疾病早期的患者的生物体液或环境样本中进行检测。本文综述了各种病毒检测技术,并介绍了基于珠粒的分析、数字分析和基于孔的传感等典型技术,这三种现代方法在速度和灵敏度方面提高了病毒检测的性能。