André J L, Deschamps J P, Gueguen R
Clin Exp Hypertens A. 1986;8(4-5):661-7. doi: 10.3109/10641968609046582.
Familial resemblance of blood pressure (BP) was studied in 545 families of which 370 included natural children, 24 adopted children and 151 both natural and adopted children. Mean values of four automatic BP measurements (Dinamap 845) were converted into age (adult) or height (children) and sex adjusted scores. BP was compared between parents and randomly chosen index children. A significant resemblance of BP was observed between natural children and their parents: r = 0.24 for systolic BP, r = 0.29 for diastolic BP, (n = 272 p greater than 0.05). BP of adopted children did not resemble that of their foster parents except for a significant correlation to BP of the adopting mothers (n = 46). Weight, heart rate, age and time of common life shared did not influence the results. The relative contribution of genetic and common environmental factors to BP correlation between family members could not be evaluated in this study. BP of children whose parents have high BP should be monitored regularly.
对545个家庭的血压(BP)家族相似性进行了研究,其中370个家庭包含亲生子女,24个家庭包含领养子女,151个家庭既有亲生子女又有领养子女。将四次自动血压测量值(Dinamap 845)的平均值转换为年龄(成人)或身高(儿童)以及经性别调整的分数。比较了父母与随机选择的指标儿童之间的血压。观察到亲生子女与其父母之间的血压存在显著相似性:收缩压r = 0.24,舒张压r = 0.29,(n = 272,p大于0.05)。领养子女的血压与其养父母的血压不相似,不过与领养母亲的血压存在显著相关性(n = 46)。体重、心率、年龄以及共同生活的时间并未影响结果。本研究无法评估遗传因素和共同环境因素对家庭成员间血压相关性的相对贡献。父母患有高血压的儿童的血压应定期监测。