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基线虚弱状况与接受腰椎退行性疾病后路腰椎间融合术患者的高级护理设施出院率:7153 例患者病例的多中心登记分析,比较风险分析指数与 5 因素改良虚弱指数。

Baseline Frailty and Discharge to Advanced Care Facilities in Patients Undergoing Lumbar Interbody Fusion for Lumbar Degenerative Disease: A Multicenter Registry Analysis of 7153 Patient Cases Comparing the Risk Analysis Index to the 5-Factor Modified Frailty Index.

机构信息

Department of Neurosurgery, University of New Mexico Hospital (UNMH), Albuquerque, New Mexico, USA; Department of Neurosurgery, Bowers Neurosurgical Frailty and Outcomes Data Science Lab, Albuquerque, New Mexico, USA.

Department of Neurosurgery, University of New Mexico Hospital (UNMH), Albuquerque, New Mexico, USA; Department of Neurosurgery, Bowers Neurosurgical Frailty and Outcomes Data Science Lab, Albuquerque, New Mexico, USA.

出版信息

World Neurosurg. 2023 Dec;180:e77-e83. doi: 10.1016/j.wneu.2023.08.027. Epub 2023 Aug 12.

Abstract

OBJECTIVE

To evaluate the impact of frailty, as measured by the 5-factor modified Frailty Index (mFI-5) and the Risk Analysis Index (RAI), on advanced care facility discharge (FD) in patients who underwent lumbar fusion for lumbar degenerative spine disease.

METHODS

The American College of Surgeons National Surgical Quality Improvement Program (2012-2020) was queried for adults (≥18 years) undergoing lumbar fusion for lumbar degenerative disease. Descriptive statistics and univariate crosstabulation were used to assess baseline demographics, preoperative comorbidities, and postoperative outcomes. Receiver operating characteristic curve analysis was used to assess the discriminative threshold of the mFI-5 and RAI on FD within this population.

RESULTS

The median patient age in this study cohort (N = 7153) was 56 years and FD occurred in 7.3% of cases. Receiver operating characteristic curve analysis demonstrated that both the mFI-5 and the RAI accurately predicted FD (C-statistics: mFI-5: 0.627; RAI: 0.746). DeLong's test found that the RAI had superior discrimination when compared to the mFI-5 (P < 0.0001).

CONCLUSIONS

RAI is a reliable predictor of FD in lumbar degenerative disease patients who underwent lumbar interbody fusion and demonstrated superior discrimination compared to the mFI-5. Identification of patients at risk for FD may facilitate more precise risk stratification to enable better preoperative decision-making and help set more realistic expectations of care.

摘要

目的

评估 5 因素改良衰弱指数(mFI-5)和风险分析指数(RAI)测量的衰弱对接受腰椎融合术治疗腰椎退行性脊柱疾病患者进入高级护理机构(FD)的影响。

方法

查询美国外科医师学会国家手术质量改进计划(2012-2020 年),纳入接受腰椎融合术治疗腰椎退行性疾病的成年人(≥18 岁)。采用描述性统计和单变量交叉表评估基线人口统计学、术前合并症和术后结局。使用受试者工作特征曲线分析评估 mFI-5 和 RAI 在该人群中对 FD 的区分阈值。

结果

本研究队列(N=7153)患者的中位年龄为 56 岁,7.3%的患者发生 FD。受试者工作特征曲线分析表明,mFI-5 和 RAI 均可准确预测 FD(C 统计量:mFI-5:0.627;RAI:0.746)。DeLong 检验发现 RAI 的鉴别能力优于 mFI-5(P<0.0001)。

结论

RAI 是腰椎退行性疾病患者接受腰椎椎间融合术后 FD 的可靠预测指标,其鉴别能力优于 mFI-5。识别有 FD 风险的患者可能有助于更精确地进行风险分层,从而更好地进行术前决策,并帮助设定更现实的护理期望。

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