Elliott S, Davies P
Clin Radiol. 1986 Sep;37(5):495-8. doi: 10.1016/s0009-9260(86)80074-5.
It is usually assumed as a result of experiments that post-obstructive and hydronephrotic atrophy are due to raised intrapelvic pressure. In acute ureteric obstruction raised intrapelvic pressure is associated with renal colic; the absence of pain in chronic obstruction has been a stumbling block to acceptance of the back pressure theory. In ureteric obstruction due to bladder carcinoma the complete spectrum of nephrographic appearances ranging from those of high pressure obstruction to low pressure obstruction is seen in the absence of pain. This shows that acute ureteric obstruction may be painless and therefore post-obstructive and hydronephrotic atrophy may be preceded in man by a raised intrapelvic pressure. This removes the stumbling block.
通常根据实验假设,梗阻后和肾积水性萎缩是由于肾盂内压力升高所致。在急性输尿管梗阻时,肾盂内压力升高与肾绞痛有关;慢性梗阻时无疼痛一直是接受反压理论的绊脚石。在膀胱癌导致的输尿管梗阻中,在没有疼痛的情况下可以看到从高压梗阻到低压梗阻的完整肾造影表现谱。这表明急性输尿管梗阻可能是无痛的,因此在人类中,梗阻后和肾积水性萎缩可能先于肾盂内压力升高出现。这就消除了绊脚石。