Shanghai Food Safety and Engineering Technology Research Center, Bor S. Luh Food Safety Research Center, Key Lab of Urban Agriculture (South), School of Agriculture & Biology, Shanghai Jiao Tong University, Shanghai, China.
Yili Innovation Center, Inner Mongolia Yili Industrial Group Co., Ltd, Hohhot, China.
Crit Rev Food Sci Nutr. 2024 Nov;64(32):11985-12008. doi: 10.1080/10408398.2023.2245893. Epub 2023 Aug 13.
Anthocyanins (ACNs) are one of the subgroups of flavonoids and getting intensive attraction due to the nutritional values. However, their application of ACNs is limited due to their poor stability and bioavailability. Accordingly, nanoencapsulation has been developed to enhance its stability and bio-efficacy. This review focuses on the nano-technique applications of delivery systems that be used for ACNs stabilization, with an emphasis on physicochemical stability and health benefits. ACNs incorporated with delivery systems in forms of nano-particles and fibrils can achieve advanced functions, such as improved stability, enhanced bioavailability, and controlled release. Also, the toxicological evaluation of nano delivery systems is summarized. Additionally, this review summarizes the challenges and suggests the further perspectives for the further application of ACNs delivery systems in food and medical fields.
花色苷(Anthocyanins,ACNs)是类黄酮的一个亚组,由于其营养价值而受到广泛关注。然而,由于其稳定性和生物利用度差,其应用受到限制。因此,已经开发出纳米封装技术来提高其稳定性和生物功效。本综述重点介绍了用于花色苷稳定化的输送系统的纳米技术应用,重点介绍了物理化学稳定性和健康益处。以纳米颗粒和纤维的形式与输送系统结合的花色苷可以实现先进的功能,例如提高稳定性、增强生物利用度和控制释放。此外,还总结了纳米输送系统的毒理学评价。此外,本综述总结了挑战,并为花色苷输送系统在食品和医疗领域的进一步应用提出了进一步的展望。