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作为门静脉性胆管病严重并发症的确定性治疗方法的Roux-en-Y胆管重建术。病例系列。

Roux-en-Y biliary reconstruction as a definitive treatment for serious complications of portal biliopathy. Case series.

作者信息

Ochoa Gabriela, Marino Carlo, Dib Martín, Briceño Eduardo, Martinez Jorge A, Jarufe Nicolas

机构信息

Department of Digestive Surgery, Pontificia Universidad Católica de Chile's Hospital, Santiago, Chile.

Department of Digestive Surgery, Pontificia Universidad Católica de Chile's Hospital, Santiago, Chile.

出版信息

Int J Surg Case Rep. 2023 Sep;110:108571. doi: 10.1016/j.ijscr.2023.108571. Epub 2023 Jul 27.

Abstract

INTRODUCTION AND IMPORTANCE

Portal biliopathy (PB) is an abnormality of the biliary tree wall due to extrahepatic portal hypertension. Among the complications of portal biliopathy are digestive bleeding, jaundice, and cholangitis. Surgical treatment is an exception when medical management is not possible.

CASE PRESENTATION

This is a case series study of four patients with severe PB complications requiring surgical management in our center from 2005 to 2016. Two of them had previous surgical procedures related to portal hypertension. All presented with severe biliary stenosis and recurrent cholangitis, and two also had massive upper gastrointestinal bleeding. Because of endoscopic management failure, a Roux-en-Y hepaticojejunostomy was performed in all cases. Two patients presented morbidity Clavien-Dindo>IIIA, requiring reoperation. During follow-up, no one developed other complications related to PB.

DISCUSSION

Surgical treatment for PB complications is a challenge and mainly implies a portosystemic shunt as a first step. When it fails, an alternative is perform a biliodigestive anastomoses, with high risk of bleeding given the prominent collaterals present in the hepatoduodenal pedicle secondary to portal cavernomatosis.

CONCLUSION

Our patients after YRGB didn't present new complications due to PB. The surgery could be a definite solution for PB complications. It has only been made for selective cases because it implies high complexity and risk.

摘要

引言与重要性

门静脉性胆管病(PB)是一种由于肝外门静脉高压导致的胆管壁异常。门静脉性胆管病的并发症包括消化道出血、黄疸和胆管炎。当药物治疗无效时,手术治疗是一种例外情况。

病例报告

这是一项对2005年至2016年期间在我们中心需要手术治疗的4例严重PB并发症患者的病例系列研究。其中2例曾接受过与门静脉高压相关的手术。所有患者均表现为严重的胆管狭窄和复发性胆管炎,2例还出现大量上消化道出血。由于内镜治疗失败,所有病例均行Roux-en-Y肝空肠吻合术。2例患者出现Clavien-Dindo>IIIA级并发症,需要再次手术。在随访期间,没有人出现与PB相关的其他并发症。

讨论

PB并发症的手术治疗是一项挑战,主要意味着首先进行门体分流术。当分流术失败时,另一种选择是进行胆肠吻合术,鉴于门静脉海绵样变性继发于肝十二指肠蒂的明显侧支循环,出血风险很高。

结论

我们的患者在接受YRGB手术后未出现因PB导致的新并发症。手术可能是PB并发症的确切解决方案。仅对选择性病例进行手术,因为手术具有高复杂性和高风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f17/10448269/ffb29cda9603/gr1.jpg

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