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Editorial: Targeting metabolism to activate T cells and enhance the efficacy of checkpoint blockade immunotherapy in solid tumors.社论：靶向代谢以激活T细胞并增强实体瘤中检查点阻断免疫疗法的疗效
Front Immunol. 2023 Jul 27;14:1247178. doi: 10.3389/fimmu.2023.1247178. eCollection 2023.
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本文引用的文献

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A novel signature predicts prognosis and immunotherapy in lung adenocarcinoma based on cancer-associated fibroblasts.一种基于癌相关成纤维细胞的新型标志物可预测肺腺癌的预后和免疫治疗反应。
Front Immunol. 2023 May 31;14:1201573. doi: 10.3389/fimmu.2023.1201573. eCollection 2023.
2
Metabolic reprogramming of cancer-associated fibroblasts in pancreatic cancer contributes to the intratumor heterogeneity of PET-CT.胰腺癌中癌症相关成纤维细胞的代谢重编程促成了PET-CT的肿瘤内异质性。
Comput Struct Biotechnol J. 2023 Apr 7;21:2631-2639. doi: 10.1016/j.csbj.2023.04.003. eCollection 2023.
3
Prognostic signatures of sphingolipids: Understanding the immune landscape and predictive role in immunotherapy response and outcomes of hepatocellular carcinoma.鞘脂标志物的预后特征：了解免疫图谱及其在预测肝癌免疫治疗反应和结局中的作用。
Front Immunol. 2023 Mar 17;14:1153423. doi: 10.3389/fimmu.2023.1153423. eCollection 2023.
4
Metabolic plasticity and regulation of T cell exhaustion.T 细胞耗竭的代谢可塑性和调控。
Immunology. 2022 Dec;167(4):482-494. doi: 10.1111/imm.13575. Epub 2022 Sep 30.
5
Rewiring mitochondrial metabolism to counteract exhaustion of CAR-T cells.重编线粒体代谢以对抗 CAR-T 细胞耗竭。
J Hematol Oncol. 2022 Mar 28;15(1):38. doi: 10.1186/s13045-022-01255-x.
6
Prosurvival IL-7-Stimulated Weak Strength of mTORC1-S6K Controls T Cell Memory via Transcriptional FOXO1-TCF1-Id3 and Metabolic AMPKα1-ULK1-ATG7 Pathways.IL-7 刺激的生存促进弱 mTORC1-S6K 力量通过转录 FOXO1-TCF1-Id3 和代谢 AMPKα1-ULK1-ATG7 途径控制 T 细胞记忆。
J Immunol. 2022 Jan 1;208(1):155-168. doi: 10.4049/jimmunol.2100452. Epub 2021 Dec 6.
7
The Importance of Cellular Metabolic Pathways in Pathogenesis and Selective Treatments of Hematological Malignancies.细胞代谢途径在血液系统恶性肿瘤发病机制及选择性治疗中的重要性
Front Oncol. 2021 Nov 10;11:767026. doi: 10.3389/fonc.2021.767026. eCollection 2021.
8
IL-33 activates mTORC1 and modulates glycolytic metabolism in CD8 T cells.IL-33 激活 mTORC1 并调节 CD8 T 细胞的糖酵解代谢。
Immunology. 2022 Jan;165(1):61-73. doi: 10.1111/imm.13404. Epub 2021 Aug 31.
9
Interleukin-34 Reprograms Glycolytic and Osteoclastic Rheumatoid Arthritis Macrophages via Syndecan 1 and Macrophage Colony-Stimulating Factor Receptor.白细胞介素 34 通过 syndecan 1 和巨噬细胞集落刺激因子受体重编程糖酵解和破骨细胞类风湿关节炎巨噬细胞。
Arthritis Rheumatol. 2021 Nov;73(11):2003-2014. doi: 10.1002/art.41792. Epub 2021 Sep 22.
10
IL-23 and IL-1β Drive Human Th17 Cell Differentiation and Metabolic Reprogramming in Absence of CD28 Costimulation.IL-23 和 IL-1β 在缺乏 CD28 共刺激的情况下驱动人 Th17 细胞分化和代谢重编程。
Cell Rep. 2018 Mar 6;22(10):2642-2653. doi: 10.1016/j.celrep.2018.02.044.

Editorial: Targeting metabolism to activate T cells and enhance the efficacy of checkpoint blockade immunotherapy in solid tumors.

作者信息

Xia Zhijia, Chen Shi, He Miao, Li Benhua, Deng Yayuan, Yi Lin, Li Xiaosong

机构信息

Department of General, Visceral, and Transplant Surgery, Ludwig-Maximilians-University Munich, Munich, Germany.

Clinical Molecular Medicine Testing Center, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.

出版信息

Front Immunol. 2023 Jul 27;14:1247178. doi: 10.3389/fimmu.2023.1247178. eCollection 2023.

DOI:10.3389/fimmu.2023.1247178
PMID:37575246
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10415066/
Abstract
摘要