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妊娠期间年轻加纳人复发性嗜铬细胞瘤的管理。

Management of recurrent pheochromocytoma in pregnancy in a young Ghanaian.

机构信息

Endocrinology Unit, Department of Medicine and Therapeutics, University of Ghana Medical School.

Endocrinology Unit, Department of Medicine and Therapeutics, Korle Bu Teaching Hospital.

出版信息

Ghana Med J. 2022 Dec;56(4):340-344. doi: 10.4314/gmj.v56i4.14.

DOI:10.4314/gmj.v56i4.14
PMID:37575627
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10416282/
Abstract

The co-existence of pheochromocytoma and pregnancy is rare, with poor maternal and foetal outcomes. This is a case report of a young Ghanaian woman with a pre-existing diagnosis of recurrent pheochromocytoma who became pregnant and experienced elevated blood pressure in the third trimester with proteinuria and abnormal liver function. She was managed as an in-patient and delivered a live baby via caesarean section at 34 weeks after detecting intra-uterine growth restriction. Management of such cases by a multidisciplinary team is recommended for optimal outcomes.

摘要

嗜铬细胞瘤合并妊娠较为罕见,母婴结局均较差。本文报告了一例年轻加纳籍妇女,既往诊断为复发性嗜铬细胞瘤,妊娠后在孕晚期出现血压升高,伴蛋白尿和肝功能异常。该患者收住院治疗,在发现胎儿宫内生长受限后 34 周经剖宫产娩出活婴。建议多学科团队管理此类病例,以获得最佳结局。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08cb/10416282/c3ca5e26af13/GMJ5604-0340Fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08cb/10416282/8aa0497eb12f/GMJ5604-0340Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08cb/10416282/c3ca5e26af13/GMJ5604-0340Fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08cb/10416282/8aa0497eb12f/GMJ5604-0340Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08cb/10416282/c3ca5e26af13/GMJ5604-0340Fig2.jpg

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本文引用的文献

1
A Misleading Presentation of Pheochromocytoma in Pregnancy: A Case Report.妊娠期间嗜铬细胞瘤的误诊表现:一例报告
Medeni Med J. 2021;36(1):69-74. doi: 10.5222/MMJ.2021.29660. Epub 2021 Mar 26.
2
Maternal and fetal outcomes in phaeochromocytoma and pregnancy: a multicentre retrospective cohort study and systematic review of literature.《妊娠合并嗜铬细胞瘤:一项多中心回顾性队列研究和文献系统评价》。
Lancet Diabetes Endocrinol. 2021 Jan;9(1):13-21. doi: 10.1016/S2213-8587(20)30363-6. Epub 2020 Nov 26.
3
Recurrence Rate of Sporadic Pheochromocytomas After Curative Adrenalectomy: A Systematic Review and Meta-analysis.
根治性肾上腺切除术后散发性嗜铬细胞瘤的复发率:一项系统评价和荟萃分析。
J Clin Endocrinol Metab. 2021 Jan 23;106(2):588-597. doi: 10.1210/clinem/dgaa794.
4
Recurrence of Pheochromocytoma With Metastases After Resection of Primary Tumor.原发性肿瘤切除术后伴转移的嗜铬细胞瘤复发
Cureus. 2020 May 28;12(5):e8328. doi: 10.7759/cureus.8328.
5
Pheochromocytoma and Pregnancy.嗜铬细胞瘤与妊娠。
Endocrinol Metab Clin North Am. 2019 Sep;48(3):605-617. doi: 10.1016/j.ecl.2019.05.006. Epub 2019 Jun 13.
6
Impact of maternal pheochromocytoma on the fetus and neonate.母亲嗜铬细胞瘤对胎儿和新生儿的影响。
Gynecol Endocrinol. 2019 Apr;35(4):280-286. doi: 10.1080/09513590.2018.1540568. Epub 2019 Jan 6.
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Initial clinical presentation and spectrum of pheochromocytoma: a study of 94 cases from a single center.嗜铬细胞瘤的初始临床表现及谱系:来自单一中心的94例病例研究
Endocr Connect. 2018 Jan;7(1):186-192. doi: 10.1530/EC-17-0321. Epub 2017 Dec 7.
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ENDOCRINOLOGY IN PREGNANCY: Pheochromocytoma in pregnancy: case series and review of literature.妊娠内分泌学:妊娠期间嗜铬细胞瘤:病例系列和文献复习。
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Pheochromocytoma after Cesarean Section.剖宫产术后嗜铬细胞瘤
Int J Prev Med. 2016 Mar 10;7:60. doi: 10.4103/2008-7802.178534. eCollection 2016.
10
MANAGEMENT OF CATECHOLAMINE-SECRETING TUMORS IN PREGNANCY: A REVIEW.妊娠期儿茶酚胺分泌肿瘤的管理:综述
Endocr Pract. 2016 Mar;22(3):357-70. doi: 10.4158/EP151009.RA. Epub 2015 Nov 4.