Malik Mona J, Pasha Muhammad Nabeel, Salib Victor
Internal Medicine, Univeristy of California, Riverside, Riverside, USA.
Pulmonary and Critical Care Medicine, One Brooklyn Health, New York, USA.
Cureus. 2023 Jul 11;15(7):e41736. doi: 10.7759/cureus.41736. eCollection 2023 Jul.
Leukocytoclastic vasculitis, also known as hypersensitivity angiitis, is a cutaneous, small vessel vasculitis of the dermal capillaries and venules. The predominant clinical presentation is palpable purpura. Multiple medications can cause leukocytoclastic vasculitis, as well as autoimmune diseases, infections, and malignancy. The disease process may be limited to only the skin or a manifestation of a systemic vasculitis or process. Treatment is centered on symptom management. Our patient is a 60-year-old female who presented with bilateral dry and wet tender ulcerations. She was previously treated with paclizumab.
白细胞破碎性血管炎,也称为超敏性血管炎,是一种累及真皮毛细血管和小静脉的皮肤小血管炎。主要临床表现为可触及的紫癜。多种药物可导致白细胞破碎性血管炎,自身免疫性疾病、感染及恶性肿瘤也可引发。疾病过程可能仅局限于皮肤,或是全身性血管炎或病症的一种表现。治疗以症状管理为核心。我们的患者是一名60岁女性,出现双侧干湿交替的压痛性溃疡。她之前接受过帕博利珠单抗治疗。