Sharma Vishal, Singhal Mayank, Sharma Alka, Kumar Vivek
Department of Medicine, University College of Medical Sciences, University of Delhi, Delhi, India.
J Infect Dev Ctries. 2012 Dec 15;6(12):895-6. doi: 10.3855/jidc.2278.
Cutaneous manifestations are uncommon with malaria. These include urticaria, purpura fulminans, and petechial rash. We report on a series of three patients from a single family who had an urticarial rash with fever that was subsequently diagnosed to be caused by malaria. Urticarial rash has been previously reported with both falciparum and vivax malaria infections. Although the exact pathogenesis is not clear urticarial rash might be related with IgE mediated mast cell degranulation.
皮肤表现并不常见于疟疾。这些表现包括荨麻疹、暴发性紫癜和瘀点疹。我们报告了来自同一个家庭的三名患者,他们出现了伴有发热的荨麻疹皮疹,随后被诊断为由疟疾引起。先前已有关于恶性疟和间日疟感染伴发荨麻疹皮疹的报道。虽然确切的发病机制尚不清楚,但荨麻疹皮疹可能与IgE介导的肥大细胞脱颗粒有关。