Fletcher Tom E, Beeching N J
Tropical and Infectious Disease Unit, Royal Liverpool University Hospital, Liverpool, UK.
J R Army Med Corps. 2013 Sep;159(3):158-66. doi: 10.1136/jramc-2013-000112. Epub 2013 Jul 11.
Malaria is a life-threatening disease, with its largest impact being due to Plasmodium falciparum infection in Africa. Military populations continue to be at a high risk of malaria and reported case series have frequently revealed poor compliance with preventative measures. The symptoms of malaria are non-specific and its management depends on awareness of the diagnosis and early recognition and treatment. This is aided by new and simple rapid diagnostic tests, but these should not replace the examination of blood films if these are available. Artemisinin combination therapy provides a more rapid and dependable cure of uncomplicated P falciparum infection, with artesunate now being the drug of choice in severe infection.
疟疾是一种危及生命的疾病,其最大影响源于非洲的恶性疟原虫感染。军人仍然面临着较高的疟疾风险,报告的病例系列经常显示对预防措施的依从性较差。疟疾的症状不具有特异性,其治疗取决于对诊断的认识以及早期识别和治疗。新型简单快速诊断检测对此有帮助,但如果有血涂片检查,这些检测不应取代血涂片检查。青蒿素联合疗法能更快速、可靠地治愈非复杂性恶性疟原虫感染,青蒿琥酯现在是重症感染的首选药物。