Aillal Melainine, Khazri Abdelhafidh, Al-Hoshani Nawal, Boufahja Fehmi, Beyrem Hamouda, Yahya Lafdal Mohamed
University of Nouakchott, Faculty of Sciences and Technology, New University Campus, BP 5026, Nouakchott, Mauritania.
Laboratory of Environment Biomonitoring, Coastal Ecology Unit, Faculty of Sciences of Bizerte, University of Carthage, Zarzouna, Tunisia.
Saudi J Biol Sci. 2023 Aug;30(8):103718. doi: 10.1016/j.sjbs.2023.103718. Epub 2023 Jun 28.
Inevitably, high concentrations of iron, the most widely produced ore globally, can be found in aquatic environments. To assess the toxicity of iron on aquatic organisms, specimens were subjected to microparticles derived from two types of iron ore (hematite and magnetite) at four different concentrations (0.5, 1, 1.5, and 5 g/L). The findings revealed that both types of iron ore were absorbed by clams in a concentration-dependent manner. Biomarkers analysis demonstrated significant and organ-specific impacts on the health of the clams caused by these microparticles, which was further supported by computational analyses on bioavailability. Within seven days of exposure, changes were observed in the activities of several enzymes, including catalase, acetylcholinesterase, and glutathione S-transferases, as well as in the rate of lipid peroxidation in both the digestive gland and gills. This study provides an environmental perspective on the toxicological effects of iron ore microparticles.
不可避免地，在水生环境中会发现高浓度的铁，铁是全球产量最高的矿石。为了评估铁对水生生物的毒性，将标本置于来自两种铁矿石（赤铁矿和磁铁矿）的微粒中，浓度分别为四种不同水平（0.5、1、1.5和5克/升）。研究结果表明，两种类型的铁矿石均以浓度依赖的方式被蛤蜊吸收。生物标志物分析表明，这些微粒对蛤蜊的健康产生了显著的、器官特异性的影响，生物有效性的计算分析进一步支持了这一点。在暴露的七天内，观察到几种酶的活性发生了变化，包括过氧化氢酶、乙酰胆碱酯酶和谷胱甘肽S-转移酶，同时消化腺和鳃中的脂质过氧化速率也发生了变化。本研究从环境角度提供了铁矿石微粒毒理学效应的相关情况。
