实体肿瘤恶性肿瘤所致获得性凝血因子VIII抑制剂
Acquired factor VIII inhibitor caused by solid tumor malignancy.
作者信息
de Bear Olivia, McLean Karen, Siedel Jean, Rolston Aimee
机构信息
Gynecologic Oncology Division, Department of Obstetrics and Gynecology, Michigan Medicine, 1500 East Medical Center Drive, Ann Arbor, MI 48109, United States.
Department of Gynecologic Oncology and Department of Pharmacology & Therapeutics, Roswell Park Comprehensive Cancer Center, Elm & Carlton Streets, Buffalo, NY 14263, United States.
出版信息
Gynecol Oncol Rep. 2023 Jun 7;48:101217. doi: 10.1016/j.gore.2023.101217. eCollection 2023 Aug.
•Factor VIII inhibitor can be acquired in gynecologic and other malignancies.•The disorder can develop along any timeline of malignancy diagnosis.•Common presentation is uncontrolled bleeding not managed by common interventions.•Treatment requires hemostatic control and an immunosuppressive regimen.
•获得性血友病A可发生于妇科及其他恶性肿瘤中。
•该疾病可在恶性肿瘤诊断后的任何时间出现。
•常见表现为常规干预措施无法控制的出血。
•治疗需要实现止血控制并采用免疫抑制方案。
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