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无症状患者颈动脉多普勒超声检查的指征——我们的检查开单是否正确?

Indications for carotid Doppler ultrasound in asymptomatic patients - are we ordering it correctly?

作者信息

da Silva Alcides Alves, Moro André Brusamolin, Toregeani Jeferson Freitas

机构信息

Centro Universitário da Fundação Assis Gurgacz - FAG, Cascavel, PR, Brasil.

Universidade Estadual do Oeste do Paraná - UNIOESTE, Cascavel, PR, Brasil.

出版信息

J Vasc Bras. 2023 Aug 7;22:e20220084. doi: 10.1590/1677-5449.202200841. eCollection 2023.

DOI:10.1590/1677-5449.202200841
PMID:37576728
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10421587/
Abstract

BACKGROUND

Carotid arteries are frequently the site of pathologies, the most common being atherosclerosis, which may result in the formation of plaques, causing stenosis. Doppler ultrasound is currently the exam of choice for assessment of the carotid arteries in asymptomatic patients to screen for and diagnose vascular lesions. Current guidelines recommend screening patients who have risk factors for carotid stenosis and who are able and willing to undergo medical treatment and/or carotid intervention. Screening asymptomatic patients in the general adult population who have no significant risk factors is not recommended.

OBJECTIVES

To assess whether medical experts rely on the literature to request Doppler ultrasound for screening.

METHODS

A retrospective selection of patients was performed based on requests for carotid ultrasound. The data collected were computed and analyzed using RStudio version 1.3.959.

RESULTS

The request was evaluated as appropriate as long as the patients presented at least one risk factor for carotid plaques. Fifty-five out of 152 patients met criteria for carotid screening. The most frequent indication in the study population was vascular check-up. Arterial hypertension was the most prevalent risk factor. Vascular surgery specialists were more likely to order the exam correctly (odds ratio for correct indications: 3.52 [CI 1.14 - 10.87], with p=0.02). The rate of correct Doppler ultrasound requests was 36% (95%CI 29 to 42%).

CONCLUSIONS

An excess of requests for carotid ultrasound screening was found in this study. Vascular surgeons more often requested the test correctly.

摘要

背景

颈动脉常常是病变发生的部位,最常见的是动脉粥样硬化,这可能导致斑块形成,进而引起狭窄。目前,多普勒超声是无症状患者颈动脉评估的首选检查方法,用于筛查和诊断血管病变。现行指南建议对有颈动脉狭窄危险因素且能够并愿意接受药物治疗和/或颈动脉干预的患者进行筛查。不建议对无明显危险因素的一般成年无症状人群进行筛查。

目的

评估医学专家是否依据文献要求进行多普勒超声筛查。

方法

根据颈动脉超声检查申请对患者进行回顾性选择。收集的数据使用RStudio 1.3.959版本进行计算和分析。

结果

只要患者至少有一项颈动脉斑块危险因素,该检查申请就被评估为合理。152例患者中有55例符合颈动脉筛查标准。研究人群中最常见的指征是血管检查。动脉高血压是最普遍的危险因素。血管外科专家更有可能正确开具检查单(正确指征的比值比:3.52 [CI 1.14 - 10.87],p = 0.02)。正确的多普勒超声检查申请率为36%(95%CI 29至42%)。

结论

本研究发现颈动脉超声筛查申请过多。血管外科医生更常正确开具该项检查申请。

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Society for Vascular Surgery clinical practice guidelines for management of extracranial cerebrovascular disease.血管外科学会颅外脑血管疾病管理临床实践指南
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Screening for Asymptomatic Carotid Artery Stenosis: US Preventive Services Task Force Recommendation Statement.无症状颈动脉狭窄筛查:美国预防服务工作组推荐声明。
JAMA. 2021 Feb 2;325(5):476-481. doi: 10.1001/jama.2020.26988.
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Global and regional prevalence, burden, and risk factors for carotid atherosclerosis: a systematic review, meta-analysis, and modelling study.全球及区域颈动脉粥样硬化的流行率、负担及风险因素:一项系统评价、荟萃分析及建模研究。
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Curr Med Res Opin. 2020 Mar;36(3):361-365. doi: 10.1080/03007995.2020.1713075. Epub 2020 Jan 13.
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Misconceptions regarding the adequacy of best medical intervention alone for asymptomatic carotid stenosis.关于无症状颈动脉狭窄仅靠最佳医学干预是否充分的误解。
J Vasc Surg. 2020 Jan;71(1):257-269. doi: 10.1016/j.jvs.2019.04.490. Epub 2019 Sep 26.
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[Duplex ultrasound in cerebrovascular disease - asymptomatic carotid stenosis].[脑血管疾病中的双功超声——无症状性颈动脉狭窄]
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Carotid Ultrasound Examinations: Indications Correlated With Abnormal Findings.颈动脉超声检查:与异常发现相关的适应症
Ultrasound Q. 2018 Sep;34(3):183-189. doi: 10.1097/RUQ.0000000000000371.
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2017 ESC Guidelines on the Diagnosis and Treatment of Peripheral Arterial Diseases, in collaboration with the European Society for Vascular Surgery (ESVS): Document covering atherosclerotic disease of extracranial carotid and vertebral, mesenteric, renal, upper and lower extremity arteriesEndorsed by: the European Stroke Organization (ESO)The Task Force for the Diagnosis and Treatment of Peripheral Arterial Diseases of the European Society of Cardiology (ESC) and of the European Society for Vascular Surgery (ESVS).2017年欧洲心脏病学会(ESC)与欧洲血管外科学会(ESVS)合作制定的外周动脉疾病诊断和治疗指南:涵盖颅外颈动脉和椎动脉、肠系膜、肾、上肢和下肢动脉粥样硬化疾病的文件 认可机构:欧洲卒中组织(ESO) 欧洲心脏病学会(ESC)和欧洲血管外科学会(ESVS)外周动脉疾病诊断和治疗特别工作组
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Editor's Choice - Management of Atherosclerotic Carotid and Vertebral Artery Disease: 2017 Clinical Practice Guidelines of the European Society for Vascular Surgery (ESVS).编辑推荐——动脉粥样硬化性颈动脉和椎动脉疾病的管理:欧洲血管外科学会(ESVS)2017年临床实践指南
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Rev Col Bras Cir. 2017 May-Jun;44(3):293-301. doi: 10.1590/0100-69912017003012.