Grover Shekhar, Anand Tanu, Kishore Jugal, Sinha D N, Malhotra Sumit, Dhawan Priyanka, Goel Sonu
Maulana Azad Institute of Dental Sciences, New Delhi, India.
Indian Council of Medical Research, New Delhi, India.
Prev Med Rep. 2023 Jul 20;35:102281. doi: 10.1016/j.pmedr.2023.102281. eCollection 2023 Oct.
Hypertension (high blood pressure) during pregnancy has significant implications on maternal and perinatal morbidity and mortality. Tobacco use during pregnancy amplifies this burden and increases the risk of hypertensive disorders along with adverse birth outcomes. The current study aimed to evaluate the joint risk atpopulation-level of tobacco use and hypertension among pregnant women in India.
Data of 32,428 "currently pregnant" women aged 15-49 years was obtained from the National Family Health Survey (NFHS-4) 2015-16to estimate bivariate (tobacco user vs. non-user) and binomial logistic regression analysis in order to get odds ratios of having hypertension. The analysis included socio-demographic variables such as the respondent's age, type of residence, wealth index, and education status.
Prevalence of hypertension among pregnant tobacco users (7.5%) was significantly higher than that of non-users (6.1%). The unadjusted odds of having hypertension were 1.17 (95% CI: 1.02-1.35) times among tobacco users than non-users and increased with age (p < 0.001) and in rural areas (p = 0.02) after adjusting for other covariates. However, it varied inversely with education status (p > 0.05; NS) and wealth quintile (p = 0.01).
The present study identifies the higher co-existence of hypertension among tobacco-using pregnant women and highlights the need for tobacco control/cessation and hypertension prevention and management during pregnancy considering socio-demographic disparities.
孕期高血压对孕产妇及围产期发病率和死亡率有重大影响。孕期吸烟会加重这一负担,增加患高血压疾病的风险以及不良分娩结局的风险。本研究旨在评估印度孕妇中吸烟与高血压在人群层面的联合风险。
从2015 - 2016年全国家庭健康调查(NFHS - 4)中获取了32428名年龄在15 - 49岁的“当前怀孕”女性的数据,以估计双变量(吸烟者与非吸烟者)和二项逻辑回归分析,从而得出患高血压的比值比。分析纳入了社会人口统计学变量,如受访者的年龄、居住类型、财富指数和教育状况。
孕期吸烟女性的高血压患病率(7.5%)显著高于非吸烟女性(6.1%)。在未调整的情况下,吸烟女性患高血压的几率是非吸烟女性的1.17倍(95%置信区间:1.02 - 1.35),在调整其他协变量后,随着年龄增长(p < 0.001)以及在农村地区(p = 0.02),患高血压的几率增加。然而,其与教育状况(p > 0.05;无显著性差异)和财富五分位数(p = 0.01)呈反向变化。
本研究发现吸烟孕妇中高血压的共存情况更为普遍,并强调鉴于社会人口统计学差异,在孕期需要进行烟草控制/戒烟以及高血压的预防和管理。